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Details

Stereochemistry RACEMIC
Molecular Formula C22H28NO3
Molecular Weight 354.4626
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of BEVONIUM

SMILES

C[N+]1(C)CCCCC1COC(=O)C(O)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=UHUMRJKDOOEQIG-UHFFFAOYSA-N
InChI=1S/C22H28NO3/c1-23(2)16-10-9-15-20(23)17-26-21(24)22(25,18-11-5-3-6-12-18)19-13-7-4-8-14-19/h3-8,11-14,20,25H,9-10,15-17H2,1-2H3/q+1

HIDE SMILES / InChI
Molecular Formula C22H27NO3
Molecular Weight 353.4547
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Bevonium is a parasympatolytic antimuscarinic compound. It possesses spasmolytic properties. The use of the drug is discontinued.

Originator

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Antagonist
2778
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
ACABEL

Approved Use

Acabel (Bevonium methyl sulfate) is parasympatolytic drug with well balanced action on the neuromuscular device. Possesses broncho-and spasmolytic properties. Acabel is indicated for bronchial asthma, peptic ulcer of a stomach and duodenum, pylorospasm, postoperative spastic pains, spastic locks, cholestasia, cholecystitis, cholangitis, postcholecystectomy syndrome, chronic hepatopathy and pancreatitis, various diseases of kidneys and urinary tract. Prenatal and puerperal pains, dysmenorrhea, adnexitis, endometritis, dysfunction of ovaries, tumor of genitalias.
PubMed

PubMed

TitleDatePubMed
Patents

Patents

20050261242
4
BE616951
2

Sample Use Guides

In Vivo Use Guide
Form of release of medicine: Acabel: tablets on 50 mg, candles on 30 pieces in packaging. Acabel compositum: tablets (bevonium methyl sulfate — 0,05 g, Dipyronum — 0,25 g); candles (bevonium methyl sulfate — 0,03 g, Dipyronum — 1 g); ampoules on 5 ml (bevonium methyl sulfate — 0,0025 g, Dipyronum — 2,5 g). Use: Acabel appoint inside 1 — 2 tablet 2 — 3 times a day, candles (only the adult) — on 1 piece 2 — 3 times a day. Intramusculary or intravenously slowly enter on 1/2 — 1 ampoule of an akabel difficult 3 once a day.
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:43:08 UTC 2023
Edited
by admin
on Fri Dec 15 15:43:08 UTC 2023
Record UNII
34B0471E08
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BEVONIUM
WHO-DD  
Common Name English
2-(HYDROXYMETHYL)-1,1-DIMETHYLPIPERIDINIUM BENZILATE
Systematic Name English
BEVONIUM CATION
Common Name English
Bevonium [WHO-DD]
Common Name English
PIPERIDINIUM, 2-(((2-HYDROXY-2,2-DIPHENYLACETYL)OXY)METHYL)-1,1-DIMETHYL-
Systematic Name English
BEVONIUM ION
Common Name English
Classification Tree Code System Code
WHO-VATC QA03AB13
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
WHO-ATC A03AB13
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
WHO-VATC QA03CA06
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
WHO-ATC A03DA03
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
WHO-VATC QA03DA03
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
NCI_THESAURUS C66880
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
WHO-ATC A03CA06
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
Code System Code Type Description
PUBCHEM
31800
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
DRUG CENTRAL
3024
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
CAS
33371-53-8
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
NCI_THESAURUS
C73804
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
SMS_ID
100000085006
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
EPA CompTox
DTXSID0048341
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
EVMPD
SUB00794MIG
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
FDA UNII
34B0471E08
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
DRUG BANK
DB13542
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
MESH
C000002
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
WIKIPEDIA
BEVONIUM
Created by admin on Fri Dec 15 15:43:08 UTC 2023 , Edited by admin on Fri Dec 15 15:43:08 UTC 2023
PRIMARY
Related Record Type Details
Structure of BEVONIUM METILSULFATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of BEVONIUM
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