Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C19H26F2N2O2 |
| Molecular Weight | 352.4187 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN1CC2(CCN(CCC3=CC(F)=CC=C3F)CC2)O[C@H](C)C1=O
InChI
InChIKey=KALIKXMQWFLZKB-CQSZACIVSA-N
InChI=1S/C19H26F2N2O2/c1-3-23-13-19(25-14(2)18(23)24)7-10-22(11-8-19)9-6-15-12-16(20)4-5-17(15)21/h4-5,12,14H,3,6-11,13H2,1-2H3/t14-/m1/s1
| Molecular Formula | C19H26F2N2O2 |
| Molecular Weight | 352.4187 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 19:23:51 GMT 2025
by
admin
on
Wed Apr 02 19:23:51 GMT 2025
|
| Record UNII |
2L6QPL2USH
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| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
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Common Name | English | ||
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Preferred Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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1838622-25-5
Created by
admin on Wed Apr 02 19:23:51 GMT 2025 , Edited by admin on Wed Apr 02 19:23:51 GMT 2025
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300000042410
Created by
admin on Wed Apr 02 19:23:51 GMT 2025 , Edited by admin on Wed Apr 02 19:23:51 GMT 2025
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118561036
Created by
admin on Wed Apr 02 19:23:51 GMT 2025 , Edited by admin on Wed Apr 02 19:23:51 GMT 2025
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PRIMARY | |||
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2L6QPL2USH
Created by
admin on Wed Apr 02 19:23:51 GMT 2025 , Edited by admin on Wed Apr 02 19:23:51 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET -> AGONIST |
Emax=90% Relative maximum effect induced by stimulation with DAMGO. MOR functionality (EC50) measuring cyclic AMP (cAMP) on CHO-K1 cells.
EC50
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ENANTIOMER -> ENANTIOMER |
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TARGET -> AGONIST |
Binding assay using [3H]-DAMGO as radioligand.
BINDING
Ki
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TARGET -> INHIBITOR |
Ki
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RACEMATE -> ENANTIOMER |
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![Structure of 9-[2-(2,5-Difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one, (2S)-](/img/80c97511-928f-4ca9-8eba-d03b29df52f0.svg "Structure of 9-[2-(2,5-Difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one, (2S)-")
![Structure of 1-Oxa-4,9-diazaspiro[5.5]undecan-3-one, 9-[2-(2,5-difluorophenyl)ethyl]-4-ethyl-2-methyl-](/img/3c202b68-738a-426c-83b7-dbded089b88d.svg "Structure of 1-Oxa-4,9-diazaspiro[5.5]undecan-3-one, 9-[2-(2,5-difluorophenyl)ethyl]-4-ethyl-2-methyl-")
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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