U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C18H27NO
Molecular Weight 273.4131
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3-METHOXYPHENCYCLIDINE

SMILES

COC1=CC=CC(=C1)C2(CCCCC2)N3CCCCC3

InChI

InChIKey=BQQSZHHKGPOXLN-UHFFFAOYSA-N
InChI=1S/C18H27NO/c1-20-17-10-8-9-16(15-17)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h8-10,15H,2-7,11-14H2,1H3

HIDE SMILES / InChI

Molecular Formula C18H27NO
Molecular Weight 273.4131
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: CHEMBL2094124
Sources: ncbi.nlm.nih.gov/pubmed/23527166
20.0 nM [Ki]
Target ID: CHEMBL228
Sources: ncbi.nlm.nih.gov/pubmed/23527166
216.0 nM [Ki]
Target ID: Q99720|||Q7Z653
Gene ID: 10280.0
Gene Symbol: SIGMAR1
Target Organism: Homo sapiens (Human)
Sources: ncbi.nlm.nih.gov/pubmed/23527166
42.0 nM [Ki]
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:11:41 GMT 2023
Edited
by admin
on Sat Dec 16 11:11:41 GMT 2023
Record UNII
28A91R606X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
3-METHOXYPHENCYCLIDINE
Common Name English
PIPERIDINE, 1-(1-(3-METHOXYPHENYL)CYCLOHEXYL)-
Systematic Name English
1-(1-(3-METHOXYPHENYL)CYCLOHEXYL)PIPERIDINE
Systematic Name English
3-MEO-PCP
Common Name English
Classification Tree Code System Code
WIKIPEDIA NMDA receptor antagonist
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
WIKIPEDIA Designer-drugs-3-MeO-PCP
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
Code System Code Type Description
PUBCHEM
11778080
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
PRIMARY
EVMPD
SUB178325
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
PRIMARY
FDA UNII
28A91R606X
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
PRIMARY
CAS
72242-03-6
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
PRIMARY
EPA CompTox
DTXSID50222578
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
PRIMARY
SMS_ID
100000163994
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
PRIMARY
WIKIPEDIA
3-MEO-PCP
Created by admin on Sat Dec 16 11:11:41 GMT 2023 , Edited by admin on Sat Dec 16 11:11:41 GMT 2023
PRIMARY 3-Hydroxyphencyclidine (3-HO-PCP) is a dissociative anesthetic that has been sold online as a designer drug.[1] 3-HO-PCP binds to the NMDA and opioid receptors.
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET -> INHIBITOR
Ki
TARGET -> INHIBITOR
Channel blocker
UNCOMPETITIVE
Ki
Related Record Type Details
ACTIVE MOIETY