U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C9H11N
Molecular Weight 133.1903
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-AMINOINDANE

SMILES

NC1CC2=C(C1)C=CC=C2

InChI

InChIKey=LMHHFZAXSANGGM-UHFFFAOYSA-N
InChI=1S/C9H11N/c10-9-5-7-3-1-2-4-8(7)6-9/h1-4,9H,5-6,10H2

HIDE SMILES / InChI

Molecular Formula C9H11N
Molecular Weight 133.1903
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

PubMed

PubMed

TitleDatePubMed
Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties.
2004 Dec 6
Steady-state pharmacokinetics and pharmacodynamics of CHF3381, a novel antineuropathic pain agent, in healthy subjects.
2005 Apr
Indantadol, a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain.
2007 Sep
Synthesis, dopaminergic profile, and molecular dynamics calculations of N-aralkyl substituted 2-aminoindans.
2008 Mar 15
Synthesis and pharmacological evaluation of schiff bases of 4-(2-aminophenyl)-morpholines.
2009 Jul
Analgesic effect of Lepidium sativum Linn. (Chandrashura) in experimental animals.
2010 Jul
The neuroprotective mechanism of 1-(R)-aminoindan, the major metabolite of the anti-parkinsonian drug rasagiline.
2010 Mar
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:41:59 GMT 2023
Edited
by admin
on Sat Dec 16 01:41:59 GMT 2023
Record UNII
1P810SQ3EY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2-AMINOINDANE
Systematic Name English
2,3-DIHYDRO-1H-INDEN-2-AMINE
Systematic Name English
1H-INDEN-2-AMINE, 2,3-DIHYDRO-
Systematic Name English
INDANE-2-YLAMINE
Systematic Name English
J80.606D
Code English
2-INDANAMINE
Systematic Name English
(2,3-DIHYDRO-1H-INDEN-2-YL)AMINE
Systematic Name English
2-AI
Common Name English
2-INDANYLAMINE
Systematic Name English
2-AMINOINDAN
Systematic Name English
INDAN-2-AMINE
Systematic Name English
2-AMINO-2,3-DIHYDRO-1H-INDENE
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-2-AI
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
Code System Code Type Description
FDA UNII
1P810SQ3EY
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
EVMPD
SUB181269
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
CAS
2975-41-9
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
SMS_ID
100000166971
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
EPA CompTox
DTXSID40183902
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
ECHA (EC/EINECS)
221-021-3
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
WIKIPEDIA
2-Aminoindan
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
PUBCHEM
76310
Created by admin on Sat Dec 16 01:41:59 GMT 2023 , Edited by admin on Sat Dec 16 01:41:59 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY
SD Rats (male)
IN-VIVO
Scientific Literature
ACTIVE MOIETY
Analgesic potency (ED50) in male mice (s.c.): 15.0 +/- 1.8 mg/kg (as 2-aminoindane HCL)
IN-VIVO
Scientific Literature