2-AMINOINDAN HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H11N.ClH
Molecular Weight	169.651
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.NC1CC2=C(C1)C=CC=C2

InChI

InChIKey=XEHNLVMHWYPNEQ-UHFFFAOYSA-N

InChI=1S/C9H11N.ClH/c10-9-5-7-3-1-2-4-8(7)6-9;/h1-4,9H,5-6,10H2;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C9H11N
Molecular Weight	133.1903
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
Alpha-2c adrenergic receptor 37 Target ID: CHEMBL1916 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Binding Agent 1064	41.0 nM [Ki]
Alpha-2b adrenergic receptor 27 Target ID: CHEMBL1942 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Binding Agent 1064	211.0 nM [Ki]
Alpha-2a adrenergic receptor 63 Target ID: CHEMBL1867 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Binding Agent 1064	134.0 nM [Ki]
Norepinephrine transporter 191 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Substrate 661	86.0 nM [EC50]
Dopamine transporter 180 Target ID: CHEMBL238 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Substrate 661	439.0 nM [EC50]

PubMed

Title	Date	PubMed
Synthesis, dopaminergic profile, and molecular dynamics calculations of N-aralkyl substituted 2-aminoindans.	2008 Mar 15	18166467
[Analysis of designer drugs detected in the products purchased in fiscal year 2006].	2008 Oct	18827471
Analgesic and anti-inflammatory activity of amifostine, DRDE-07, and their analogs, in mice.	2010 Feb	20606831

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 12:01:27 GMT 2023` Edited by `admin` on `Sat Dec 16 12:01:27 GMT 2023`
Record UNII	PT8MYB7QQ8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-AMINOINDAN HYDROCHLORIDE

Common Name

English

NSC-78117

Code

English

1H-INDEN-2-AMINE, 2,3-DIHYDRO-, HYDROCHLORIDE (1:1)

Systematic Name

English

2-INDANAMINE, HYDROCHLORIDE

Systematic Name

English

2-AI (HYDROCHLORIDE)

Common Name

English

INDAN-2-YLAMINE HYDROCHLORIDE

Systematic Name

English

2-AMINOINDAN, HCL

Common Name

English

NSC-48663

Code

English

Code System Code Type Description

ECHA (EC/EINECS)

219-048-0