ARAGUANOSINE

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NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H13N5O5
Molecular Weight	283.2407
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ARAGUANOSINE

Structure Search

SMILES

NC1=NC2=C(N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O)C(=O)N1

InChI

InChIKey=NYHBQMYGNKIUIF-FJFJXFQQSA-N

InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C10H13N5O5
Molecular Weight	283.2407
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:42:14 GMT 2025` Edited by `admin` on `Mon Mar 31 22:42:14 GMT 2025`
Record UNII	0Z99WX0GPF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-76352

Preferred Name

English

ARAGUANOSINE

Common Name

English

ARA-GUANOSINE

Common Name

English

GUANINE ARABINOSIDE

Common Name

English

9-.BETA.-D-ARABINOFURANOSYLGUANINE

Common Name

English

2-AMINO-6-HYDROXY-9-(.BETA.-D-ARABINOFURANOSYL)PURINE

Systematic Name

English

NELARABINE METABOLITE (ARA-GUANOSINE)

Common Name

English

Code System Code Type Description

PUBCHEM

135499520

Created by admin on Mon Mar 31 22:42:14 GMT 2025 , Edited by admin on Mon Mar 31 22:42:14 GMT 2025

PRIMARY

EPA CompTox

DTXSID301019130

Created by admin on Mon Mar 31 22:42:14 GMT 2025 , Edited by admin on Mon Mar 31 22:42:14 GMT 2025

PRIMARY

CAS

38819-10-2

Created by admin on Mon Mar 31 22:42:14 GMT 2025 , Edited by admin on Mon Mar 31 22:42:14 GMT 2025

PRIMARY

NSC

76352

Created by admin on Mon Mar 31 22:42:14 GMT 2025 , Edited by admin on Mon Mar 31 22:42:14 GMT 2025

PRIMARY

FDA UNII

0Z99WX0GPF

Created by admin on Mon Mar 31 22:42:14 GMT 2025 , Edited by admin on Mon Mar 31 22:42:14 GMT 2025

PRIMARY

Related Record Type Details


					0Z99WX0GPF

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Comments:

Plasma protein binding increased as ara-G concentrations increased.

Interaction Type:

BINDING

Amount:

Related Record Type Details


					60158CV180

PRODRUG -> METABOLITE ACTIVE

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				SINGLE DOSE ADMINISTRATION

Tmax	PHARMACOKINETIC				SINGLE DOSE ADMINISTRATION