Details
Stereochemistry | ACHIRAL |
Molecular Formula | C14H28O2 |
Molecular Weight | 228.3709 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCC(O)=O
InChI
InChIKey=TUNFSRHWOTWDNC-UHFFFAOYSA-N
InChI=1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)
Molecular Formula | C14H28O2 |
Molecular Weight | 228.3709 |
Charge | 0 |
Count |
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Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/9323584 | https://elibrary.ru/item.asp?id=5420911 | http://www.tuscany-diet.net/lipids/list-of-fatty-acids/myristic/ | https://www.ncbi.nlm.nih.gov/pubmed/19154695 | https://www.ncbi.nlm.nih.gov/pubmed/20634506DOI: 10.1016/0378-5173(89)90003-3https://www.ewg.org/skindeep/ingredient/706137/SODIUM_MYRISTATE/ | Burdock, G.A. (1997) Encyclopedia of Food and Color Additives, page 2575, retrieved from: https://books.google.ru/books?id=NtaR9i3hYCYC | Igoe, R.S. (2013) Dictionary of Food Ingredients, page 129, retrieved from: https://books.google.ru/books?id=WEKEBwAAQBAJ
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9323584 | https://elibrary.ru/item.asp?id=5420911 | http://www.tuscany-diet.net/lipids/list-of-fatty-acids/myristic/ | https://www.ncbi.nlm.nih.gov/pubmed/19154695 | https://www.ncbi.nlm.nih.gov/pubmed/20634506DOI: 10.1016/0378-5173(89)90003-3https://www.ewg.org/skindeep/ingredient/706137/SODIUM_MYRISTATE/ | Burdock, G.A. (1997) Encyclopedia of Food and Color Additives, page 2575, retrieved from: https://books.google.ru/books?id=NtaR9i3hYCYC | Igoe, R.S. (2013) Dictionary of Food Ingredients, page 129, retrieved from: https://books.google.ru/books?id=WEKEBwAAQBAJ
Sodium myristate is the sodium salt of myristic acid. It is used in the food as the binder, emulsifier and anticaking agent. It is one of the commonly occurring soaps. It is used in cosmetic as a cleansing and emulsifying agent.
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3335863
Curator's Comment: Known to be CNS penetrant in rats. Human data not available.
Originator
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: CHEMBL5088 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20920594 |
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Target ID: CHEMBL2021749 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20920594 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Diagnostic | Unknown Approved UseUnknown |
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Sources: https://www.ncbi.nlm.nih.gov/pubmed/26800189 |
Diagnostic | Unknown Approved UseUnknown |
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Inactive ingredient | Volu-Firm Approved UseUnknown |
PubMed
Title | Date | PubMed |
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Influence of a fatty acid on duodenal motility. | 1975 |
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Thermodynamics of binding water and solute to powdered long-chain salts of fatty acids. | 1994 Oct |
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Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 Jul 14 |
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Adipose tissue fatty acids in men from two populations with different cardiovascular risk: the LiVicordia study. | 1999 May |
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Fatty acid binding to human serum albumin: new insights from crystallographic studies. | 1999 Nov 23 |
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Evaluation of skin damage caused by percutaneous absorption enhancers using fractal analysis. | 2000 Apr |
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Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate. | 2001 |
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Expression, purification, and biochemical properties of EFA6, a Sec7 domain-containing guanine exchange factor for ADP-ribosylation factor 6 (ARF6). | 2001 |
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Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. | 2001 Apr 27 |
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Regulation of Golgi structure and function by ARF-like protein 1 (Arl1). | 2001 Dec |
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Differential actions of PKA and PKC in the regulation of glutamate release by group III mGluRs in the entorhinal cortex. | 2001 Feb |
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Cellular and viral Fos proteins are degraded by different proteolytic systems. | 2001 Feb 22 |
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Behenic acid is a cholesterol-raising saturated fatty acid in humans. | 2001 Jan |
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The neuronal calcium sensor family of Ca2+-binding proteins. | 2001 Jan 1 |
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Drosophila embryos lacking N-myristoyltransferase have multiple developmental defects. | 2001 Jan 15 |
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HIV-1 Nef promotes survival of myeloid cells by a Stat3-dependent pathway. | 2001 Jul 6 |
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Copper-catalyzed coupling of arylboronic acids and amines. | 2001 Jun 28 |
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Self-assembly of regular hollow icosahedra in salt-free catanionic solutions. | 2001 Jun 7 |
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Imidazoline I(1) receptor-induced activation of phosphatidylcholine-specific phospholipase C elicits mitogen-activated protein kinase phosphorylation in PC12 cells. | 2001 Mar |
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Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine receptor clustering. | 2001 Mar 9 |
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N-terminal myristylation of HBV preS1 domain enhances receptor recognition. | 2001 May |
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Optimization of carbohydrate fatty acid ester synthesis in organic media by a lipase from Candida antarctica. | 2001 Sep 20 |
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Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers. | 2002 Apr 19 |
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Myristyl and palmityl acylation of pI 5.1 carboxylesterase from porcine intestine and liver. | 2002 Feb |
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Serum free fatty acid pattern and risk of myocardial infarction: a case-control study. | 2002 Jan |
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[Fatty acid-induced reversal of general anesthesia: chain length-dependence of antagonizing potencies of fatty acids]. | 2002 Jan |
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The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase. | 2002 Jan 4 |
Patents
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2981363
Rous sarcoma virus-transformed cells were labeled for 2 h with either 1 mCi of [3H]palmitic acid or 0.2 mCi of [3H]myristic acid, and p60src was isolated by immunoprecipitation. The incorporation of [3H]myristic acid into p60src was ca. 100-fold greater than the incorporation of [3H]palmitic acid.
Substance Class |
Chemical
Created
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0I3V7S25AW
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Validated (UNII)
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NCI_THESAURUS |
C68421
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CFR |
21 CFR 172.860
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NCI_THESAURUS |
C68388
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LOINC |
75103-2
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CFR |
21 CFR 357.210
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LOINC |
35157-7
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JECFA EVALUATION |
MYRISTIC ACID
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LOINC |
47783-6
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DSLD |
3280 (Number of products:15)
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100000154392
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SUB128589
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11005
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m7689
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544-63-8
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1356758
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DTXSID6021666
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DB08231
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1448990
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30807
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1090
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CHEMBL111077
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28875
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0I3V7S25AW
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D019814
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MYRISTIC ACID
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C68393
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5028
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208-875-2
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0I3V7S25AW
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1313976
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5686
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Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT |
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LIPID -> FATTY ACID |
G Jurriens and ACJ Kroesen, J Am Oil Chem Soc, 42(9)(1965)(average value).
Range values as of FAO/WHO Codex Alimentarius Committee on commercial fats and oils.(unspecified percent)
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT |
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LIPID -> FATTY ACID | |||
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LIPID -> FATTY ACID |
JB Rossell and co-workers; JAOCS62(2), 221-230(1985).
Range weight is a mean.
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SALT/SOLVATE -> PARENT | |||
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LIPID -> FATTY ACID |
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LIPID -> FATTY ACID | |||
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SALT/SOLVATE -> PARENT |
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PARENT -> CONSTITUENT ALWAYS PRESENT | |||
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SALT/SOLVATE -> PARENT | |||
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LIPID -> FATTY ACID |
MAY BE PRESENT
USP
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SALT/SOLVATE -> PARENT |
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LIPID -> FATTY ACID |
Values are % of weight of fatty acid composition.
O?Connor, RT, Herb, SF; J Am Oil Chem Soc 47, 186A, 195A, 197A(1970)(range)
Brignoli, CA et al: J Am Diet Assoc 68, 224(1976)(average
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PARENT -> CONSTITUENT ALWAYS PRESENT | |||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT |
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Related Record | Type | Details | ||
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ACTIVE MOIETY |
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