MYRISTIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H28O2
Molecular Weight	228.3709
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CCCCCCCCCCCCCC(O)=O

InChI

InChIKey=TUNFSRHWOTWDNC-UHFFFAOYSA-N

InChI=1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)

HIDE SMILES / InChI

Molecular Formula	C14H28O2
Molecular Weight	228.3709
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Sodium myristate is the sodium salt of myristic acid. It is used in the food as the binder, emulsifier and anticaking agent. It is one of the commonly occurring soaps. It is used in cosmetic as a cleansing and emulsifying agent.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Fatty acid desaturase 2 5	Activator 1,430
Sphingolipid delta(4)-desaturase DES1 5	Activator 1,430

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2,578
Gallbladder cancer 3	Diagnostic	Not Provided 504	Unknown
Sepsis 71	Diagnostic	Phase II 1,132	Unknown
Sunburns 22	Inactive ingredient	Approved 8,429	Volu-Firm

PubMed

Show entries

Title	Date	PubMed
The effect of additives on the oral mucosal absorption of human calcitonin in rats.	1988 Jun	3171881
The mitigating effects of phosphatidylcholines on bile salt- and lysophosphatidylcholine-induced membrane damage.	1992 Aug	1359088
Effect of Protonation on the Solution and Phase Behavior of Aqueous Sodium Myristate.	2000 Nov 1	11082246
Longitudinal study of fatty acids in plasma and erythrocyte phospholipids during pregnancy.	2001	11565197
Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells.	2001 Aug	11424085

Showing 1 to 5 of 19 entries

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Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Rous sarcoma virus-transformed cells were labeled for 2 h with either 1 mCi of [3H]palmitic acid or 0.2 mCi of [3H]myristic acid, and p60src was isolated by immunoprecipitation. The incorporation of [3H]myristic acid into p60src was ca. 100-fold greater than the incorporation of [3H]palmitic acid.