Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H27O2.Na |
| Molecular Weight | 250.3533 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCC(=O)[O-].[Na+]
InChI
InChIKey=JUQGWKYSEXPRGL-UHFFFAOYSA-M
InChI=1S/C14H28O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;/h2-13H2,1H3,(H,15,16);/q;+1/p-1
| Molecular Formula | C14H27O2 |
| Molecular Weight | 227.3635 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/9323584 | https://elibrary.ru/item.asp?id=5420911 | http://www.tuscany-diet.net/lipids/list-of-fatty-acids/myristic/ | https://www.ncbi.nlm.nih.gov/pubmed/19154695 | https://www.ncbi.nlm.nih.gov/pubmed/20634506DOI: 10.1016/0378-5173(89)90003-3https://www.ewg.org/skindeep/ingredient/706137/SODIUM_MYRISTATE/ | Burdock, G.A. (1997) Encyclopedia of Food and Color Additives, page 2575, retrieved from: https://books.google.ru/books?id=NtaR9i3hYCYC | Igoe, R.S. (2013) Dictionary of Food Ingredients, page 129, retrieved from: https://books.google.ru/books?id=WEKEBwAAQBAJ
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9323584 | https://elibrary.ru/item.asp?id=5420911 | http://www.tuscany-diet.net/lipids/list-of-fatty-acids/myristic/ | https://www.ncbi.nlm.nih.gov/pubmed/19154695 | https://www.ncbi.nlm.nih.gov/pubmed/20634506DOI: 10.1016/0378-5173(89)90003-3https://www.ewg.org/skindeep/ingredient/706137/SODIUM_MYRISTATE/ | Burdock, G.A. (1997) Encyclopedia of Food and Color Additives, page 2575, retrieved from: https://books.google.ru/books?id=NtaR9i3hYCYC | Igoe, R.S. (2013) Dictionary of Food Ingredients, page 129, retrieved from: https://books.google.ru/books?id=WEKEBwAAQBAJ
Sodium myristate is the sodium salt of myristic acid. It is used in the food as the binder, emulsifier and anticaking agent. It is one of the commonly occurring soaps. It is used in cosmetic as a cleansing and emulsifying agent.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Comparative quantitative fatty acid analysis of triacylglycerols using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and gas chromatography. | 2001 |
|
| Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channels. | 2001 |
|
| Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. | 2001 Apr 27 |
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| Fatty acid synthesis in African trypanosomes: a solution to the myristate mystery. | 2001 Aug |
|
| Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells. | 2001 Aug |
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| Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids. | 2001 Aug 20 |
|
| beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket. | 2001 Aug 21 |
|
| Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis. | 2001 Aug 7 |
|
| Regulation of Golgi structure and function by ARF-like protein 1 (Arl1). | 2001 Dec |
|
| Palmitate decreases proton pumping of liver-type cytochrome c oxidase. | 2001 Dec |
|
| Characterization of the binding of Photobacterium phosphoreum P-flavin by Vibrio harveyi Luciferase. | 2001 Dec 15 |
|
| The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate. | 2001 Jan 15 |
|
| [Determination of higher fatty acids in human plasma]. | 2001 Jul |
|
| Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. | 2001 Jul |
|
| Ca2+-myristoyl switch and membrane binding of chemically acylated neurocalcins. | 2001 Jul 10 |
|
| N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons. | 2001 Jun |
|
| Expression, purification and characterization of cytochrome P450 Biol: a novel P450 involved in biotin synthesis in Bacillus subtilis. | 2001 Jun |
|
| Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets. | 2001 Jun |
|
| Regulation of G proteins by covalent modification. | 2001 Mar 26 |
|
| Acrylic resins as rate-controlling membranes in novel formulation of a nine-day 17beta-estradiol transdermal delivery system: in vitro and release modifier effect evaluation. | 2001 May |
|
| Morbid myristoylation. | 2001 May |
|
| Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. | 2001 May 18 |
|
| Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. | 2001 May 29 |
|
| Fatty acid profiles of nitrite-oxidizing bacteria reflect their phylogenetic heterogeneity. | 2001 Nov |
|
| Inhibition and regulation of rat liver L-threonine dehydrogenase by different fatty acids and their derivatives. | 2001 Nov 7 |
|
| Enzyme activity of the cytochrome P-450 monooxygenase system in the presence of single chain lipid molecules. | 2001 Nov-Dec |
|
| Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells. | 2001 Oct |
|
| Effects of incubator humidity and hen age on yolk composition in broiler hatching eggs from young breeders. | 2001 Oct |
|
| Deletion of N-terminal myristoylation site of HIV Nef abrogates both MHC-1 and CD4 down-regulation. | 2001 Oct 1 |
|
| Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450. | 2001 Oct 1 |
|
| Phosphorylation of human N-myristoyltransferase by N-myristoylated SRC family tyrosine kinase members. | 2001 Oct 19 |
|
| Rational design of diflunisal analogues with reduced affinity for human serum albumin. | 2001 Oct 31 |
|
| Propranolol increases phosphatidic acid level via activation of phospholipase D. | 2001 Sep |
|
| Rat pancreatic acinar cells express a cytosolic phospholipase D1b isoform that is not regulated by cholecystokinin. | 2001 Sep |
|
| Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14). | 2001 Sep 14 |
|
| Optimization of carbohydrate fatty acid ester synthesis in organic media by a lipase from Candida antarctica. | 2001 Sep 20 |
|
| Coexpression of proteins with methionine aminopeptidase and/or N-myristoyltransferase in Escherichia coli to increase acylation and homogeneity of protein preparations. | 2002 |
|
| Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca2+ signal transduction. | 2002 Apr 19 |
|
| Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers. | 2002 Apr 19 |
|
| Myristyl and palmityl acylation of pI 5.1 carboxylesterase from porcine intestine and liver. | 2002 Feb |
|
| Differences in the fatty acid composition of larvae and metamorphosing sea lampreys, Petromyzon marinus. | 2002 Feb |
|
| Oxidative stress induced cytokine production in isolated rat pancreatic acinar cells: effects of small-molecule antioxidants. | 2002 Feb |
|
| Enzymatic reaction of hydrogen peroxide-dependent peroxygenase cytochrome P450s: kinetic deuterium isotope effects and analyses by resonance Raman spectroscopy. | 2002 Feb 12 |
|
| Serum free fatty acid pattern and risk of myocardial infarction: a case-control study. | 2002 Jan |
|
| [Fatty acid-induced reversal of general anesthesia: chain length-dependence of antagonizing potencies of fatty acids]. | 2002 Jan |
|
| Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease. | 2002 Jan |
|
| Differences in calmodulin and calmodulin-binding proteins in phasic and tonic smooth muscles. | 2002 Jan |
|
| Permeation of a myristoylated dipeptide across the buccal mucosa: topological distribution and evaluation of tissue integrity. | 2002 Jan 1 |
|
| Interaction of bovine (BSA) and human (HSA) serum albumins with ionic surfactants: spectroscopy and modelling. | 2002 Jan 31 |
|
| The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase. | 2002 Jan 4 |
Patents
Sample Use Guides
Rous sarcoma virus-transformed cells were labeled for 2 h with either 1 mCi of [3H]palmitic acid or 0.2 mCi of [3H]myristic acid, and p60src was isolated by immunoprecipitation. The incorporation of [3H]myristic acid into p60src was ca. 100-fold greater than the incorporation of [3H]palmitic acid.
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 10:05:54 UTC 2021
by
admin
on
Sat Jun 26 10:05:54 UTC 2021
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| Record UNII |
06BLC4V0IV
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| Record Status |
Validated (UNII)
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| Record Version |
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JECFA EVALUATION |
INS-470(I)
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CODEX ALIMENTARIUS (GSFA) |
INS-470(I)
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1744165
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Sodium myristate
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06BLC4V0IV
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212-487-9
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822-12-8
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23693095
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822-12-8
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PARENT -> SALT/SOLVATE |
