Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H27O2.Na |
| Molecular Weight | 250.3527 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].CCCCCCCCCCCCCC([O-])=O
InChI
InChIKey=JUQGWKYSEXPRGL-UHFFFAOYSA-M
InChI=1S/C14H28O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;/h2-13H2,1H3,(H,15,16);/q;+1/p-1
| Molecular Formula | C14H27O2 |
| Molecular Weight | 227.363 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/9323584 | https://elibrary.ru/item.asp?id=5420911 | http://www.tuscany-diet.net/lipids/list-of-fatty-acids/myristic/ | https://www.ncbi.nlm.nih.gov/pubmed/19154695 | https://www.ncbi.nlm.nih.gov/pubmed/20634506https://www.ewg.org/skindeep/ingredient/706137/SODIUM_MYRISTATE/ | Burdock, G.A. (1997) Encyclopedia of Food and Color Additives, page 2575, retrieved from: https://books.google.ru/books?id=NtaR9i3hYCYC | Igoe, R.S. (2013) Dictionary of Food Ingredients, page 129, retrieved from: https://books.google.ru/books?id=WEKEBwAAQBAJDOI: 10.1016/0378-5173(89)90003-3
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9323584 | https://elibrary.ru/item.asp?id=5420911 | http://www.tuscany-diet.net/lipids/list-of-fatty-acids/myristic/ | https://www.ncbi.nlm.nih.gov/pubmed/19154695 | https://www.ncbi.nlm.nih.gov/pubmed/20634506https://www.ewg.org/skindeep/ingredient/706137/SODIUM_MYRISTATE/ | Burdock, G.A. (1997) Encyclopedia of Food and Color Additives, page 2575, retrieved from: https://books.google.ru/books?id=NtaR9i3hYCYC | Igoe, R.S. (2013) Dictionary of Food Ingredients, page 129, retrieved from: https://books.google.ru/books?id=WEKEBwAAQBAJDOI: 10.1016/0378-5173(89)90003-3
Ammonium myristate is passage-delaying substance. It was used as a substance for influencing gastrointestinal passage. The addition of ammonium myristate caused a delay of about 1.5 h in the transit time of the absorbing part of the gastrointestinal tract. The addition of ammonium myristate improves the availability of nitrofurantoin from a slow releasing dosage form - an average increase is 23.8% of the total amount of nitrofurantoin excreted in the urine compared to the values obtained from the reference dosage form without the additional substance. The kinetics of renal elimination of nitrofurantoin is characterized by the longer duration of urinary excretion.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Permeation kinetics of ketotifen fumarate alone and in combination with hydrophobic permeation enhancers through human cadaver epidermis. | 2000 Jul-Aug |
|
| Molecular cloning, genomic organization, and biochemical characterization of myristoyl-CoA:protein N-myristoyltransferase from Arabidopsis thaliana. | 2000 Mar 31 |
|
| Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channels. | 2001 |
|
| In vitro production of peroxynitrite by haemocytes from marine bivalves: C-ELISA determination of 3-nitrotyrosine level in plasma proteins from Mytilus galloprovincialis and Crassostrea gigas. | 2001 |
|
| Functional analysis of ADP-ribosylation factor (ARF) guanine nucleotide exchange factors Gea1p and Gea2p in yeast. | 2001 |
|
| Isolation and properties of GRP1, an ADP-ribosylation factor (ARF)-guanine nucleotide exchange protein regulated by phosphatidylinositol 3,4,5-trisphosphate. | 2001 |
|
| Expression, purification, and biochemical properties of EFA6, a Sec7 domain-containing guanine exchange factor for ADP-ribosylation factor 6 (ARF6). | 2001 |
|
| Effects of authentic and VLDL hydrolysis-derived fatty acids on vascular smooth muscle cell growth. | 2001 Apr |
|
| Carotenoid esters in vegetables and fruits: a screening with emphasis on beta-cryptoxanthin esters. | 2001 Apr |
|
| Myristoylation of human immunodeficiency virus type 1 gag protein is required for efficient env protein transportation to the surface of cells. | 2001 Apr 20 |
|
| Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. | 2001 Apr 27 |
|
| Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin. | 2001 Apr 7 |
|
| Fatty acid synthesis in African trypanosomes: a solution to the myristate mystery. | 2001 Aug |
|
| Palmitate decreases proton pumping of liver-type cytochrome c oxidase. | 2001 Dec |
|
| Isolation and structural characterization of an R-form lipopolysaccharide from Yersinia enterocolitica serotype O:8. | 2001 Feb |
|
| Differential actions of PKA and PKC in the regulation of glutamate release by group III mGluRs in the entorhinal cortex. | 2001 Feb |
|
| Cellular and viral Fos proteins are degraded by different proteolytic systems. | 2001 Feb 22 |
|
| Protein kinase C phosphorylates RGS2 and modulates its capacity for negative regulation of Galpha 11 signaling. | 2001 Feb 23 |
|
| Intraterminal Ca(2+) and spontaneous transmitter release at the frog neuromuscular junction. | 2001 Jan |
|
| Behenic acid is a cholesterol-raising saturated fatty acid in humans. | 2001 Jan |
|
| Relationship between the concentrations of plasma phospholipid stearic acid and plasma lipoprotein lipids in healthy men. | 2001 Jan |
|
| The neuronal calcium sensor family of Ca2+-binding proteins. | 2001 Jan 1 |
|
| Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol. | 2001 Jan 12 |
|
| Interaction between the unphosphorylated receptor with high affinity for IgE and Lyn kinase. | 2001 Jan 12 |
|
| Drosophila embryos lacking N-myristoyltransferase have multiple developmental defects. | 2001 Jan 15 |
|
| Influence of myristoylation, phosphorylation, and deamidation on the structural behavior of the N-terminus of the catalytic subunit of cAMP-dependent protein kinase. | 2001 Jan 9 |
|
| Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. | 2001 Jul |
|
| Cellular and subcellular localization, N-terminal acylation, and calcium binding of Caenorhabditis elegans protein phosphatase with EF-hands. | 2001 Jul 6 |
|
| N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons. | 2001 Jun |
|
| Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets. | 2001 Jun |
|
| Imidazoline I(1) receptor-induced activation of phosphatidylcholine-specific phospholipase C elicits mitogen-activated protein kinase phosphorylation in PC12 cells. | 2001 Mar |
|
| Crystallographic phasing of myristoyl-CoA-protein N-myristoyltransferase using an iodinated analog of myristoyl-CoA. | 2001 Mar |
|
| Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization. | 2001 Mar 1 |
|
| Regulation of G proteins by covalent modification. | 2001 Mar 26 |
|
| Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine receptor clustering. | 2001 Mar 9 |
|
| The effect of temperature on the fatty acids and isozymes of a psychrotrophic and two mesophilic species of Xenorhabdus, a bacterial symbiont of entomopathogenic nematodes. | 2001 May |
|
| Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. | 2001 May 29 |
|
| Fatty acid profiles of nitrite-oxidizing bacteria reflect their phylogenetic heterogeneity. | 2001 Nov |
|
| Inhibition and regulation of rat liver L-threonine dehydrogenase by different fatty acids and their derivatives. | 2001 Nov 7 |
|
| Enzyme activity of the cytochrome P-450 monooxygenase system in the presence of single chain lipid molecules. | 2001 Nov-Dec |
|
| The biology and enzymology of protein N-myristoylation. | 2001 Oct 26 |
|
| Rational design of diflunisal analogues with reduced affinity for human serum albumin. | 2001 Oct 31 |
|
| Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca2+ signal transduction. | 2002 Apr 19 |
|
| Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers. | 2002 Apr 19 |
|
| Myristyl and palmityl acylation of pI 5.1 carboxylesterase from porcine intestine and liver. | 2002 Feb |
|
| Oxidative stress induced cytokine production in isolated rat pancreatic acinar cells: effects of small-molecule antioxidants. | 2002 Feb |
|
| Enzymatic reaction of hydrogen peroxide-dependent peroxygenase cytochrome P450s: kinetic deuterium isotope effects and analyses by resonance Raman spectroscopy. | 2002 Feb 12 |
|
| Serum free fatty acid pattern and risk of myocardial infarction: a case-control study. | 2002 Jan |
|
| [Fatty acid-induced reversal of general anesthesia: chain length-dependence of antagonizing potencies of fatty acids]. | 2002 Jan |
|
| Interaction of bovine (BSA) and human (HSA) serum albumins with ionic surfactants: spectroscopy and modelling. | 2002 Jan 31 |
Patents
Sample Use Guides
Rous sarcoma virus-transformed cells were labeled for 2 h with either 1 mCi of [3H]palmitic acid or 0.2 mCi of [3H]myristic acid, and p60src was isolated by immunoprecipitation. The incorporation of [3H]myristic acid into p60src was ca. 100-fold greater than the incorporation of [3H]palmitic acid.
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:03:15 GMT 2023
by
admin
on
Fri Dec 15 19:03:15 GMT 2023
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| Record UNII |
06BLC4V0IV
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| Record Status |
Validated (UNII)
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| Record Version |
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JECFA EVALUATION |
INS-470(I)
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CODEX ALIMENTARIUS (GSFA) |
INS-470(I)
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1744165
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Sodium myristate
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06BLC4V0IV
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06BLC4V0IV
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212-487-9
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DTXSID5042455
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23693095
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822-12-8
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PARENT -> SALT/SOLVATE |
