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Details

Stereochemistry ACHIRAL
Molecular Formula C14H27O2.Na
Molecular Weight 250.3527
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM MYRISTATE

SMILES

[Na+].CCCCCCCCCCCCCC([O-])=O

InChI

InChIKey=JUQGWKYSEXPRGL-UHFFFAOYSA-M
InChI=1S/C14H28O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;/h2-13H2,1H3,(H,15,16);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula C14H27O2
Molecular Weight 227.363
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

CNS Activity

Curator's Comment: Known to be CNS penetrant in rats. Human data not available.

Originator

Sources: DOI: 10.1080/14786444108650255

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Unknown

Approved Use

Unknown
Diagnostic
Unknown

Approved Use

Unknown
Inactive ingredient
Volu-Firm

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
The mitigating effects of phosphatidylcholines on bile salt- and lysophosphatidylcholine-induced membrane damage.
1992 Aug
Thermodynamics of binding water and solute to powdered long-chain salts of fatty acids.
1994 Oct
Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha.
1999 Jul 14
Evaluation of skin damage caused by percutaneous absorption enhancers using fractal analysis.
2000 Apr
Study on the lifetime and attenuation properties of microbubbles coated with carboxylic acid salts.
2000 Nov
Effect of Protonation on the Solution and Phase Behavior of Aqueous Sodium Myristate.
2000 Nov 1
Longitudinal study of fatty acids in plasma and erythrocyte phospholipids during pregnancy.
2001
Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channels.
2001
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate.
2001
Effects of authentic and VLDL hydrolysis-derived fatty acids on vascular smooth muscle cell growth.
2001 Apr
Carotenoid esters in vegetables and fruits: a screening with emphasis on beta-cryptoxanthin esters.
2001 Apr
Thioacylation is required for targeting G-protein subunit G(o1alpha) to detergent-insoluble caveolin-containing membrane domains.
2001 Apr 15
Fatty acid synthesis in African trypanosomes: a solution to the myristate mystery.
2001 Aug
Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells.
2001 Aug
Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids.
2001 Aug 20
Overexpression of the myristoylated alanine-rich C-kinase substrate inhibits cell adhesion to extracellular matrix components.
2001 Aug 24
Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis.
2001 Aug 7
Characterization of the binding of Photobacterium phosphoreum P-flavin by Vibrio harveyi Luciferase.
2001 Dec 15
Protein kinase C phosphorylates RGS2 and modulates its capacity for negative regulation of Galpha 11 signaling.
2001 Feb 23
The neuronal calcium sensor family of Ca2+-binding proteins.
2001 Jan 1
Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol.
2001 Jan 12
The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate.
2001 Jan 15
Drosophila embryos lacking N-myristoyltransferase have multiple developmental defects.
2001 Jan 15
Influence of myristoylation, phosphorylation, and deamidation on the structural behavior of the N-terminus of the catalytic subunit of cAMP-dependent protein kinase.
2001 Jan 9
[Determination of higher fatty acids in human plasma].
2001 Jul
Molecular characterization of StCDPK1, a calcium-dependent protein kinase from Solanum tuberosum that is induced at the onset of tuber development.
2001 Jul
Cellular and subcellular localization, N-terminal acylation, and calcium binding of Caenorhabditis elegans protein phosphatase with EF-hands.
2001 Jul 6
N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons.
2001 Jun
Cox-2 inhibitory effects of naturally occurring and modified fatty acids.
2001 Jun
Imidazoline I(1) receptor-induced activation of phosphatidylcholine-specific phospholipase C elicits mitogen-activated protein kinase phosphorylation in PC12 cells.
2001 Mar
Regulation of G proteins by covalent modification.
2001 Mar 26
N-terminal myristylation of HBV preS1 domain enhances receptor recognition.
2001 May
Ca(2+)- and myristoylation-dependent association of calcineurin with phosphatidylserine.
2001 May
Morbid myristoylation.
2001 May
A fluorogenic reagent, 4-mercapto-7-methylthio-2,1,3-benzoxadiazole for carboxylic acids, designed by prediction of the fluorescence intensity.
2001 May 15
Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis.
2001 May 29
Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells.
2001 Oct
Effects of incubator humidity and hen age on yolk composition in broiler hatching eggs from young breeders.
2001 Oct
Ethanol- and nicotine-induced membrane changes in embryonic and neonatal chick brains.
2001 Oct
Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.
2001 Oct 1
The biology and enzymology of protein N-myristoylation.
2001 Oct 26
Rational design of diflunisal analogues with reduced affinity for human serum albumin.
2001 Oct 31
Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14).
2001 Sep 14
Differential effect of valproate and its Delta2- and Delta4-unsaturated metabolites, on the beta-oxidation rate of long-chain and medium-chain fatty acids.
2001 Sep 28
[Fatty acid-induced reversal of general anesthesia: chain length-dependence of antagonizing potencies of fatty acids].
2002 Jan
Adsorption and direct probing of fibrinogen and sodium myristate at the air/water interface.
2002 Jun 15
Single-step purification of myristoylated and nonmyristoylated recoverin and substrate dependence of myristoylation level.
2006 Feb 1
Self assembly of anastomosis-like superstructures in fatty acid/guanidine hydrochloride aqueous dispersions.
2010 Jan 15
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Rous sarcoma virus-transformed cells were labeled for 2 h with either 1 mCi of [3H]palmitic acid or 0.2 mCi of [3H]myristic acid, and p60src was isolated by immunoprecipitation. The incorporation of [3H]myristic acid into p60src was ca. 100-fold greater than the incorporation of [3H]palmitic acid.
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:31:37 GMT 2025
Edited
by admin
on Mon Mar 31 19:31:37 GMT 2025
Record UNII
06BLC4V0IV
Record Status Validated (UNII)
Record Version
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Name Type Language
SODIUM MYRISTATE
INCI  
INCI  
Official Name English
C 14-98/100MY, SODIUM SALT
Preferred Name English
MYRISTIC ACID, SODIUM SALT
Common Name English
E-470(I)MYRISTIC ACID, SODIUM SALT
Common Name English
TETRADECANOIC ACID, SODIUM SALT
Common Name English
INS NO.470(I)MYRISTIC ACID, SODIUM SALT
Common Name English
NIKKOL MK 140
Common Name English
INS-470(I)MYRISTIC ACID, SODIUM SALT
Common Name English
Classification Tree Code System Code
JECFA EVALUATION INS-470(I)
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-470(I)
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
Code System Code Type Description
RXCUI
1744165
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
WIKIPEDIA
Sodium myristate
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
DAILYMED
06BLC4V0IV
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
FDA UNII
06BLC4V0IV
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
ECHA (EC/EINECS)
212-487-9
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
EPA CompTox
DTXSID5042455
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
PUBCHEM
23693095
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
SMS_ID
300000054636
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
CAS
822-12-8
Created by admin on Mon Mar 31 19:31:37 GMT 2025 , Edited by admin on Mon Mar 31 19:31:37 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE