PHENAMPROMIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H26N2O
Molecular Weight	274.4011
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(=O)N(C(C)CN1CCCCC1)C2=CC=CC=C2

InChI

InChIKey=DHTRHEVNFFZCNU-UHFFFAOYSA-N

InChI=1S/C17H26N2O/c1-3-17(20)19(16-10-6-4-7-11-16)15(2)14-18-12-8-5-9-13-18/h4,6-7,10-11,15H,3,5,8-9,12-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C17H26N2O
Molecular Weight	274.4011
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: DOI: 10.1016/j.tetasy.2017.06.001 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 957, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Nordegren, T. (2002) The A-Z Encyclopedia of Alcohol and Drug Abuse, page 512, retrieved from: https://books.google.ru/books?id=4yaGePenGKgC

Phenampromide is an opioid analgesic, which is considered to be structurally similar to isomethadone. Phenampromide belongs to the ampromide family of drugs, which also include propiram and diampromide. According to the literature, (R)-phenampromide has greater analgesic potency than its (S)-enantiomer. Synthetic narcotic analgesic phenampromide is under international control according to the UN Single Convention 1961 and its amendments, Schedule I.

Originator

Approval Year

PubMed

Title	Date	PubMed
STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS. II. ABSOLUTE CONFIGURATION OF (--)-PHENAMPROMIDE.	1965-03	14332652

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:26:29 GMT 2025` Edited by `admin` on `Mon Mar 31 18:26:29 GMT 2025`
Record UNII	0600L2M6EZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PHENAMPROMIDE

Official Name

English

IDS-NP-019

Preferred Name

English

phenampromide [INN]

Common Name

English

N-(1-METHYL-2-PIPERIDIN-1-YLETHYL)-N-PHENYLPROPANAMIDE

Systematic Name

English

PHENAMPROMID

Common Name

English

PHENAMPROMIDE [MI]

Common Name

English

PROPIONANILIDE, N-(1-METHYL-2-PIPERIDINOETHYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1506