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Details

Stereochemistry RACEMIC
Molecular Formula C17H26N2O
Molecular Weight 274.4011
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENAMPROMIDE

SMILES

CCC(=O)N(C(C)CN1CCCCC1)C2=CC=CC=C2

InChI

InChIKey=DHTRHEVNFFZCNU-UHFFFAOYSA-N
InChI=1S/C17H26N2O/c1-3-17(20)19(16-10-6-4-7-11-16)15(2)14-18-12-8-5-9-13-18/h4,6-7,10-11,15H,3,5,8-9,12-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C17H26N2O
Molecular Weight 274.4011
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Phenampromide is an opioid analgesic, which is considered to be structurally similar to isomethadone. Phenampromide belongs to the ampromide family of drugs, which also include propiram and diampromide. According to the literature, (R)-phenampromide has greater analgesic potency than its (S)-enantiomer. Synthetic narcotic analgesic phenampromide is under international control according to the UN Single Convention 1961 and its amendments, Schedule I.

Approval Year

PubMed

PubMed

TitleDatePubMed
STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS. II. ABSOLUTE CONFIGURATION OF (--)-PHENAMPROMIDE.
1965 Mar
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:22:48 GMT 2023
Edited
by admin
on Fri Dec 15 16:22:48 GMT 2023
Record UNII
0600L2M6EZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHENAMPROMIDE
INN   MI  
INN  
Official Name English
phenampromide [INN]
Common Name English
IDS-NP-019
Code English
N-(1-METHYL-2-PIPERIDIN-1-YLETHYL)-N-PHENYLPROPANAMIDE
Systematic Name English
PHENAMPROMID
Common Name English
PHENAMPROMIDE [MI]
Common Name English
PROPIONANILIDE, N-(1-METHYL-2-PIPERIDINOETHYL)-
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C1506
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
DEA NO. 9638
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
Code System Code Type Description
ECHA (EC/EINECS)
204-967-1
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
WIKIPEDIA
PHENAMPROMIDE
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY Phenampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram and diampromide. It was invented in the 1960s[1] by American Cyanamid Co.[2] Although never given a general release, it was trialled and 50mg codeine ≈ 60mg phenampromide. Tests on the 2 isomers showed that all of the analgesic effects were caused by the (S) isomer.
FDA UNII
0600L2M6EZ
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
MERCK INDEX
m8593
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY Merck Index
ChEMBL
CHEMBL2104589
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
INN
948
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
EVMPD
SUB09750MIG
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
NCI_THESAURUS
C66367
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
CAS
129-83-9
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
PUBCHEM
8523
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
EPA CompTox
DTXSID10911012
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
SMS_ID
100000082209
Created by admin on Fri Dec 15 16:22:48 GMT 2023 , Edited by admin on Fri Dec 15 16:22:48 GMT 2023
PRIMARY
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SALT/SOLVATE -> PARENT
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ACTIVE MOIETY