PHENAMPROMIDE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H26N2O.ClH
Molecular Weight	310.862
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PHENAMPROMIDE HYDROCHLORIDE

Structure Search

SMILES

Cl.CCC(=O)N(C(C)CN1CCCCC1)C2=CC=CC=C2

InChI

InChIKey=AUEUUAMHKRZWEJ-UHFFFAOYSA-N

InChI=1S/C17H26N2O.ClH/c1-3-17(20)19(16-10-6-4-7-11-16)15(2)14-18-12-8-5-9-13-18;/h4,6-7,10-11,15H,3,5,8-9,12-14H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	C17H26N2O
Molecular Weight	274.4011
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: DOI: 10.1016/j.tetasy.2017.06.001 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 957, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Nordegren, T. (2002) The A-Z Encyclopedia of Alcohol and Drug Abuse, page 512, retrieved from: https://books.google.ru/books?id=4yaGePenGKgC

Phenampromide is an opioid analgesic, which is considered to be structurally similar to isomethadone. Phenampromide belongs to the ampromide family of drugs, which also include propiram and diampromide. According to the literature, (R)-phenampromide has greater analgesic potency than its (S)-enantiomer. Synthetic narcotic analgesic phenampromide is under international control according to the UN Single Convention 1961 and its amendments, Schedule I.

Originator

Approval Year

PubMed

Title	Date	PubMed
STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS. II. ABSOLUTE CONFIGURATION OF (--)-PHENAMPROMIDE.	1965-03	14332652

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:26:39 GMT 2025` Edited by `admin` on `Tue Apr 01 16:26:39 GMT 2025`
Record UNII	7M3E9Q73VE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PHENAMPROMIDE HYDROCHLORIDE

Common Name

English

PROPANAMIDE, N-(1-METHYL-2-(1-PIPERIDINYL)ETHYL)-N-PHENYL-, HYDROCHLORIDE (1:1)

Preferred Name

English

PROPIONANILIDE, N-(1-METHYL-2-PIPERIDINOETHYL)-, HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID80913321

Created by admin on Tue Apr 01 16:26:39 GMT 2025 , Edited by admin on Tue Apr 01 16:26:39 GMT 2025

PRIMARY

FDA UNII

7M3E9Q73VE

Created by admin on Tue Apr 01 16:26:39 GMT 2025 , Edited by admin on Tue Apr 01 16:26:39 GMT 2025

PRIMARY

CAS

98348-21-1

Created by admin on Tue Apr 01 16:26:39 GMT 2025 , Edited by admin on Tue Apr 01 16:26:39 GMT 2025

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PUBCHEM

3062539

Created by admin on Tue Apr 01 16:26:39 GMT 2025 , Edited by admin on Tue Apr 01 16:26:39 GMT 2025

PRIMARY

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ACTIVE MOIETY

Amount: