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Details

Stereochemistry MIXED
Molecular Formula C17H26N2O.C4H6O5
Molecular Weight 408.4886
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENAMPROMIDE MALATE

SMILES

OC(CC(O)=O)C(O)=O.CCC(=O)N(C(C)CN1CCCCC1)C2=CC=CC=C2

InChI

InChIKey=NOPCCURPBPYHNU-UHFFFAOYSA-N
InChI=1S/C17H26N2O.C4H6O5/c1-3-17(20)19(16-10-6-4-7-11-16)15(2)14-18-12-8-5-9-13-18;5-2(4(8)9)1-3(6)7/h4,6-7,10-11,15H,3,5,8-9,12-14H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)

HIDE SMILES / InChI

Molecular Formula C4H6O5
Molecular Weight 134.0874
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Molecular Formula C17H26N2O
Molecular Weight 274.4011
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Phenampromide is an opioid analgesic, which is considered to be structurally similar to isomethadone. Phenampromide belongs to the ampromide family of drugs, which also include propiram and diampromide. According to the literature, (R)-phenampromide has greater analgesic potency than its (S)-enantiomer. Synthetic narcotic analgesic phenampromide is under international control according to the UN Single Convention 1961 and its amendments, Schedule I.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
K6R3T6YCF8
Record Status Validated (UNII)
Record Version