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Details

Stereochemistry RACEMIC
Molecular Formula C13H17NO2
Molecular Weight 219.2796
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALMINOPROFEN

SMILES

CC(C(O)=O)C1=CC=C(NCC(C)=C)C=C1

InChI

InChIKey=FPHLBGOJWPEVME-UHFFFAOYSA-N
InChI=1S/C13H17NO2/c1-9(2)8-14-12-6-4-11(5-7-12)10(3)13(15)16/h4-7,10,14H,1,8H2,2-3H3,(H,15,16)

HIDE SMILES / InChI
Molecular Formula C13H17NO2
Molecular Weight 219.2796
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment: Description was created based on several sources, including http://www.ncbi.nlm.nih.gov/pubmed/2787705

Alminoprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. It has anti-inflammatory properties different from the classical NSAID. Alminoprofen possesses both antiphospholipase A2 (PLA2) activity and anti-cycloxygenase (COX) activity.

CNS Activity

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Secretory phospholipase A2, Homo sapiens
3
Target ID: Secretory phospholipase A2, Homo sapiens
Inhibitor
8297
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Approved
8429
Minalfen

Approved Use

Indications: inflammation, pain
Primary
Approved
8429
Minalfen

Approved Use

Indications: inflammation, pain
PubMed

PubMed

TitleDatePubMed
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
2010 Dec
Patents

Patents

US2016089478
3
US2016090381
3

Sample Use Guides

In Vivo Use Guide
In rheumatoid arthritis and spondylosis deformans - 200 mg (three times a day) repeated dose for 5 days.
Route of Administration: Oral
In Vitro Use Guide
Alminoprofen (10(-6)-10(-4) M) inhibited dose-dependently the chemotaxis of leukocytes induced by chemotactic factors from guinea pig neutrophils stimulated with sodium urate crystals.
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:28:08 UTC 2023
Edited
by admin
on Fri Dec 15 15:28:08 UTC 2023
Record UNII
0255AHR9GJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALMINOPROFEN
INN   JAN   MART.   MI   WHO-DD  
INN  
Official Name English
ALMINOPROFEN [MI]
Common Name English
alminoprofen [INN]
Common Name English
P-((2-METHYLALLYL)AMINO)HYDRATROPIC ACID
Common Name English
ALMINOPROFEN [MART.]
Common Name English
MINALFEN
Brand Name English
Alminoprofen [WHO-DD]
Common Name English
ALMINOPROFEN [JAN]
Common Name English
Classification Tree Code System Code
WHO-VATC QM01AE16
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
WHO-ATC M01AE16
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
NCI_THESAURUS C257
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
Code System Code Type Description
NCI_THESAURUS
C73070
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
DRUG BANK
DB13314
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
WIKIPEDIA
ALMINOPROFEN
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
RXCUI
17387
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY RxNorm
ChEMBL
CHEMBL1765293
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
EPA CompTox
DTXSID90865968
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
EVMPD
SUB05347MIG
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
PUBCHEM
2097
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
CAS
39718-89-3
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
MERCK INDEX
m1563
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY Merck Index
CHEBI
31190
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
INN
4570
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
SMS_ID
100000087441
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
FDA UNII
0255AHR9GJ
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
DRUG CENTRAL
126
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
ECHA (EC/EINECS)
254-604-6
Created by admin on Fri Dec 15 15:28:08 UTC 2023 , Edited by admin on Fri Dec 15 15:28:08 UTC 2023
PRIMARY
Related Record Type Details
Structure of ALMINOPROFEN, (S)-
ENANTIOMER -> RACEMATE
Structure of ALMINOPROFEN, (R)-
ENANTIOMER -> RACEMATE
Related Record Type Details
Structure of ALMINOPROFEN
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