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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H17NO2
Molecular Weight 219.2796
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALMINOPROFEN, (R)-

SMILES

C[C@@H](C(O)=O)C1=CC=C(NCC(C)=C)C=C1

InChI

InChIKey=FPHLBGOJWPEVME-SNVBAGLBSA-N
InChI=1S/C13H17NO2/c1-9(2)8-14-12-6-4-11(5-7-12)10(3)13(15)16/h4-7,10,14H,1,8H2,2-3H3,(H,15,16)/t10-/m1/s1

HIDE SMILES / InChI
Molecular Formula C13H17NO2
Molecular Weight 219.2796
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description
Curator's Comment: Description was created based on several sources, including http://www.ncbi.nlm.nih.gov/pubmed/2787705

Alminoprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. It has anti-inflammatory properties different from the classical NSAID. Alminoprofen possesses both antiphospholipase A2 (PLA2) activity and anti-cycloxygenase (COX) activity.

CNS Activity

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Secretory phospholipase A2, Homo sapiens
3
Target ID: Secretory phospholipase A2, Homo sapiens
Inhibitor
8297
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Approved
8429
Minalfen

Approved Use

Indications: inflammation, pain
Primary
Approved
8429
Minalfen

Approved Use

Indications: inflammation, pain
PubMed

PubMed

TitleDatePubMed
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
2010 Dec
Patents

Patents

US2016089478
3
US2016090381
3

Sample Use Guides

In Vivo Use Guide
In rheumatoid arthritis and spondylosis deformans - 200 mg (three times a day) repeated dose for 5 days.
Route of Administration: Oral
In Vitro Use Guide
Alminoprofen (10(-6)-10(-4) M) inhibited dose-dependently the chemotaxis of leukocytes induced by chemotactic factors from guinea pig neutrophils stimulated with sodium urate crystals.
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:51:16 GMT 2023
Edited
by admin
on Sat Dec 16 10:51:16 GMT 2023
Record UNII
4820D59WLM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALMINOPROFEN, (R)-
Common Name English
L-ALMINOPROFEN
Common Name English
BENZENEACETIC ACID, .ALPHA.-METHYL-4-((2-METHYL-2-PROPEN-1-YL)AMINO)-, (-)-
Systematic Name English
ALMINOPROFEN, (-)-
Common Name English
BENZENEACETIC ACID, .ALPHA.-METHYL-4-((2-METHYL-2-PROPEN-1-YL)AMINO)-, (.ALPHA.R)-
Systematic Name English
(-)-ALMINOPROFEN
Common Name English
Code System Code Type Description
FDA UNII
4820D59WLM
Created by admin on Sat Dec 16 10:51:16 GMT 2023 , Edited by admin on Sat Dec 16 10:51:16 GMT 2023
PRIMARY
PUBCHEM
76969615
Created by admin on Sat Dec 16 10:51:16 GMT 2023 , Edited by admin on Sat Dec 16 10:51:16 GMT 2023
PRIMARY
CAS
54362-71-9
Created by admin on Sat Dec 16 10:51:16 GMT 2023 , Edited by admin on Sat Dec 16 10:51:16 GMT 2023
PRIMARY
Related Record Type Details
Structure of ALMINOPROFEN
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