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Details

Stereochemistry ACHIRAL
Molecular Formula C19H20N2O2.C14H21ClN2O2.2H2O
Molecular Weight 629.187
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLOFEZONE

SMILES

O.O.CCN(CC)CCNC(=O)COC1=CC=C(Cl)C=C1.CCCCC2C(=O)N(N(C2=O)C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=FNOZOEQGHOYGSF-UHFFFAOYSA-N
InChI=1S/C19H20N2O2.C14H21ClN2O2.2H2O/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16;1-3-17(4-2)10-9-16-14(18)11-19-13-7-5-12(15)6-8-13;;/h4-13,17H,2-3,14H2,1H3;5-8H,3-4,9-11H2,1-2H3,(H,16,18);2*1H2

HIDE SMILES / InChI
Clofezone (Perclusone), an analgesic and anti-inflammatory agent, is a drug that was used to treat joint and muscular pain, mostly in rheumatic diseases. Clofezone is a compound preparation of phenylbutazone and clofexamide. Tolerance of Perclusone was very good, no side-effects were observed.

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Sample Use Guides

In Vivo Use Guide
The effectiveness and acceptability of clofezone (Perclusone) were compared with those of diclofenac in a placebo-controlled, double-blind, cross-over trial on a group of 29 out-patients suffering from osteoarthrosis of the knee or hip. Clofezone was given at a daily dosage of 1200 mg during the first week and 600 mg during the second week; the corresponding dosages of diclofenac were 150 mg and 75 mg.
Route of Administration: Oral
Name Type Language
CLOFEZONE
JAN   MART.   WHO-DD  
INN  
Official Name English
Clofezone [WHO-DD]
Common Name English
CLOFEZONE DIHYDRATE
Common Name English
ACETAMIDE, 2-(4-CHLOROPHENOXY)-N-(2-(DIETHYLAMINO)ETHYL)-, COMPD. WITH 4-BUTYL-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE, HYDRATE (1:1:2)
Systematic Name English
CLOFEZONE [MART.]
Common Name English
ANP-3260
Code English
clofezone [INN]
Common Name English
CLOFEZONE [JAN]
Common Name English
ANP 3260
Code English
Classification Tree Code System Code
WHO-VATC QM01AA05
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
NCI_THESAURUS C257
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
WHO-VATC QM02AA03
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
WHO-ATC M01AA05
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
WHO-ATC M02AA03
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
Code System Code Type Description
RXCUI
183877
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY RxNorm
NCI_THESAURUS
C77346
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
EPA CompTox
DTXSID50208852
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
SMS_ID
300000040303
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
CHEBI
8768
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
DRUG CENTRAL
4335
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
INN
2274
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
CAS
60104-29-2
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
PUBCHEM
6443874
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
WIKIPEDIA
CLOFEZONE
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
MESH
C073326
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY
FDA UNII
TPT3MH65LD
Created by admin on Fri Dec 15 16:12:39 GMT 2023 , Edited by admin on Fri Dec 15 16:12:39 GMT 2023
PRIMARY