AMMONIUM ANTHRANILATE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H6NO2.H4N
Molecular Weight	154.1665
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

[NH4+].NC1=C(C=CC=C1)C([O-])=O

InChI

InChIKey=ZRAOWOQXOMXTQN-UHFFFAOYSA-N

InChI=1S/C7H7NO2.H3N/c8-6-4-2-1-3-5(6)7(9)10;/h1-4H,8H2,(H,9,10);1H3

HIDE SMILES / InChI

Description

Sodium anthranilate is an excipient (pharmacologically inactive substance). Sodium anthranilate (Aminobenzoate sodium ,C7H6NNaO2), also known as sodium 2-aminobenzoate, is an organic amine. Aminobenzoate sodium exists as a yellow powder for use in pharmaceutical processing.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Anthranilate hydroxylase 4	Substrate 661

Conditions

Condition	Modality	Highest Phase	Product
Obesity 203	Inactive ingredient	Approved 8,429	Desoxyn
Intractable epilepsy 4	Diagnostic	Natural Metabolite	Unknown
Schizophrenia 298	Diagnostic	Natural Metabolite	Unknown

PubMed

Show entries

Title	Date	PubMed
Integral glycan sequencing of heparan sulfate and heparin saccharides.	2001	11450223
Comamonas testosteroni BR6020 possesses a single genetic locus for extradiol cleavage of protocatechuate.	2001 Aug	11495993
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.	2001 Jun	11471733
Effects of the butylated hydroxyanisole and butylated hydroxytoluene on the DNA adduct formation and arylamines N-acetyltransferase activity in human colon tumor cells.	2001 Mar-Apr	11396144
Changes in kynurenic, anthranilic, and quinolinic acid concentrations in rat brain tissue during development.	2001 May	11513477

Showing 1 to 5 of 34 entries

Previous1 2 3 4 5 6 7Next

Sample Use Guides

In Vivo Use Guide

15,000 or 30,000 ppm for the rats, and either 25,000 or 50,000 ppm for the mice, 5 days per week for 78 weeks

Route of Administration: Oral

In Vitro Use Guide

The DNA damage effects of tryptophan metabolites were analyzed using plasmid relaxation assay performed with anthranilic acid at various concentrations between 50 uM and 400 uM in the presence of plasmid DNA pSP-72. Anthranilic acid did not show any plasmid relaxation activity.

Show entries

Name

Type

Language

AMMONIUM ANTHRANILATE

Common Name

English

BENZOIC ACID, 2-AMINO-, AMMONIUM SALT (1:1)

Systematic Name

English

BENZOIC ACID, 2-AMINO-, MONOAMMONIUM SALT

Systematic Name

English

Showing 1 to 3 of 3 entries

Previous1Next

Show entries

Code System

Code

Type

Description

FDA UNII

QSN7VZ4A2M

PRIMARY

CAS

70346-37-1

PRIMARY

PUBCHEM

14399617

PRIMARY

Showing 1 to 3 of 3 entries

Previous1Next

PARENT (SALT/SOLVATE)


					0YS975XI6W

ANTHRANILIC ACID

SUBSTANCE RECORD


					QSN7VZ4A2M

AMMONIUM ANTHRANILATE

SMILES

InChI

CNS Activity

Originator

Approval Year

Targets

Conditions

PubMed

Patents

Sample Use Guides