AMMONIUM ANTHRANILATE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H6NO2.H4N
Molecular Weight	154.1665
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

[NH4+].NC1=CC=CC=C1C([O-])=O

InChI

InChIKey=ZRAOWOQXOMXTQN-UHFFFAOYSA-N

InChI=1S/C7H7NO2.H3N/c8-6-4-2-1-3-5(6)7(9)10;/h1-4H,8H2,(H,9,10);1H3

HIDE SMILES / InChI

Molecular Formula	H4N
Molecular Weight	18.0385
Charge	1
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C7H6NO2
Molecular Weight	136.128
Charge	-1
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Sodium anthranilate is an excipient (pharmacologically inactive substance). Sodium anthranilate (Aminobenzoate sodium ,C7H6NNaO2), also known as sodium 2-aminobenzoate, is an organic amine. Aminobenzoate sodium exists as a yellow powder for use in pharmaceutical processing.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Anthranilate hydroxylase 4	Substrate 661

Conditions

Condition	Modality	Highest Phase	Product
Obesity 206	Inactive ingredient	Approved 8,583	Desoxyn
Intractable epilepsy 4	Diagnostic	Natural Metabolite	Unknown
Schizophrenia 305	Diagnostic	Natural Metabolite	Unknown

PubMed

Show entries

Title	Date	PubMed
The relative catalytic efficiency of beta-lactamase catalyzed acyl and phosphyl transfer.	2001 Apr	11300697
Purification, characterization and crystallization of thermostable anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.	2001 Apr	11298741
Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana.	2001 Apr 25	11356516
Tryptophan catabolism in Brevibacterium linens as a potential cheese flavor adjunct.	2001 Aug	11518299
Fluorescence study of conformational properties of melanotropins labeled with aminobenzoic acid.	2001 Aug	11463659

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Sample Use Guides

In Vivo Use Guide

15,000 or 30,000 ppm for the rats, and either 25,000 or 50,000 ppm for the mice, 5 days per week for 78 weeks

Route of Administration: Oral

In Vitro Use Guide

The DNA damage effects of tryptophan metabolites were analyzed using plasmid relaxation assay performed with anthranilic acid at various concentrations between 50 uM and 400 uM in the presence of plasmid DNA pSP-72. Anthranilic acid did not show any plasmid relaxation activity.

Substance Class	Chemical
Record UNII	QSN7VZ4A2M
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

AMMONIUM ANTHRANILATE

Common Name

English

BENZOIC ACID, 2-AMINO-, AMMONIUM SALT (1:1)

Preferred Name

English

BENZOIC ACID, 2-AMINO-, MONOAMMONIUM SALT

Systematic Name

English

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Code System

Code

Type

Description

FDA UNII

QSN7VZ4A2M

PRIMARY

CAS

70346-37-1

PRIMARY

PUBCHEM

14399617

PRIMARY

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Related Record

Type

Details


					0YS975XI6W

ANTHRANILIC ACID

PARENT -> SALT/SOLVATE

Amount:

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SMILES

InChI

CNS Activity

Originator

Approval Year

Targets

Conditions

PubMed

Patents

Sample Use Guides