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US Approved Rx

11

Possibly Marketed Outside US

4

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Primary Target

Oxidative Stress

11

Thiamin pyrophosphokinase 1

11

carbohydrate metabolic process

11

Anthranilate hydroxylase

4

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Highest Phase

Approved

15

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Approval Year

1947

11

Unknown

4

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Condition

Thiamine deficiency

11

Intractable epilepsy

4

Obesity

4

Schizophrenia

4

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Treatment Modality

Preventing

11

Diagnostic

4

Inactive ingredient

4

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CNS Activity

CNS Penetrant

15

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Originator

Eijkman, C.

11

Fritzsche, C.J.

4

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Chemical

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CAS

15

FDA UNII

15

PUBCHEM

15

EPA CompTox

11

ECHA (EC/EINECS)

6

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ATC Level 1

ALIMENTARY TRACT AND METABOLISM

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ATC Level 2

VITAMINS

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ATC Level 3

VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12

1

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ATC Level 4

Vitamin B1, plain

1

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Substance Form

Salts, Hydrates, Esters, etc.

13

Principal Form

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Showing 1 - 10 of 15 results

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THIAMINE ION

4ABT0J945J

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

ANTHRANILIC ACID

0YS975XI6W

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Anthranilate hydroxylase

Conditions:

Intractable epilepsy

Sodium anthranilate is an excipient (pharmacologically inactive substance). Sodium anthranilate (Aminobenzoate sodium ,C7H6NNaO2), also known as sodium 2-aminobenzoate, is an organic amine. Aminobenzoate sodium exists as a yellow powder for use in ph...

armaceutical processing.

THIAMINE CAMSILATE

AS1A8DF3EU

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

THIAMINE

X66NSO3N35

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

THIAMINE HYDROBROMIDE HEMIHYDRATE

WV7TS40872

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

THIAMINE HYDROBROMIDE ANHYDROUS

K971V37HSF

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

THIAMINE BIS-LAURYLSULFATE

226A8HU328

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

THIAMINE NAPHTHALENE-1,5-DISULFONATE

ZWY7D9M9UB

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

THIAMINE BROMIDE

JIJ7B8T57F

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

THIAMINE HYDROCHLORIDE

M572600E5P

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Status:

US Approved Rx (1972)

First approved in 1947

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Thiamin pyrophosphokinase 1

Oxidative Stress

carbohydrate metabolic process

Conditions:

Thiamine deficiency

Thiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphoki...

nase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes involved in the TCA cycle and the non-oxidative part of the pentose phosphate pathway. The lack of thiamine may cause the thiamine deficiency. The classical syndrome caused primarily by thiamine deficiency in humans is beriberi, however, symptoms of thiamine deficiency also include congestive heart failure, metabolic acidosis, confusion, ataxia and seizures. Thiamine is a component of many vitamin complexes, which are approved for the treatmen and prevention of general vitamin deficiency, including the thiamine deficiency.

Showing 1 - 10 of 15 results

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