Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2998 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12213051 |
1.0 µM [IC50] | ||
Target ID: GO:0006821 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3783658 |
2.0 µM [Ki] | ||
Target ID: P51798 Gene ID: 1186.0 Gene Symbol: CLCN7 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20830208 |
39.0 µM [IC50] |
PubMed
Title | Date | PubMed |
---|---|---|
Chromium- and nickel-induced cytotoxicity in normal and transformed human keratinocytes: an investigation of pharmacological approaches to the prevention of Cr(VI)-induced cytotoxicity. | 1996 Feb |
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Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | 1997 Sep-Oct |
|
Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages. | 2002 Apr |
|
Tumour-specific activation of the sodium/iodide symporter gene under control of the glucose transporter gene 1 promoter (GTI-1.3). | 2003 May |
|
Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts. | 2004 Jul |
|
ATP binding cassette transporter ABC1 is required for the release of interleukin-1beta by P2X7-stimulated and lipopolysaccharide-primed mouse Schwann cells. | 2005 Mar |
|
Ionic currents in multidrug resistant K562 human leukemic cells. | 2005 Sep |
|
Absorption of folate by Caco-2 cells is not affected by high glucose concentration. | 2006 Dec 3 |
|
Appearance of segmental discrepancy of anion transport in rat distal colon. | 2007 Aug |
|
Functional ion channels in mouse bone marrow mesenchymal stem cells. | 2007 Nov |
|
The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2. | 2008 Jan |
|
Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. | 2010 Jan |
|
Attenuating homologous recombination stimulates an AID-induced antileukemic effect. | 2013 May 6 |
|
Functional swapping between transmembrane proteins TMEM16A and TMEM16F. | 2014 Mar 14 |
Patents
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Code System | Code | Type | Description | ||
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53005-05-3
Created by
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m4383
Created by
admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
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PRIMARY | Merck Index | ||
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DIDS
Created by
admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
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QHR3Z2PN8M
Created by
admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
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PRIMARY | |||
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4286
Created by
admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
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PRIMARY |
All of the following components must be present:
SUBSTANCE RECORD