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Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
1.0 µM [IC50]
2.0 µM [Ki]
Target ID: P51798
Gene ID: 1186.0
Gene Symbol: CLCN7
Target Organism: Homo sapiens (Human)
39.0 µM [IC50]
PubMed

PubMed

TitleDatePubMed
Chromium- and nickel-induced cytotoxicity in normal and transformed human keratinocytes: an investigation of pharmacological approaches to the prevention of Cr(VI)-induced cytotoxicity.
1996 Feb
Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds.
1997 Sep-Oct
Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages.
2002 Apr
Tumour-specific activation of the sodium/iodide symporter gene under control of the glucose transporter gene 1 promoter (GTI-1.3).
2003 May
Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts.
2004 Jul
ATP binding cassette transporter ABC1 is required for the release of interleukin-1beta by P2X7-stimulated and lipopolysaccharide-primed mouse Schwann cells.
2005 Mar
Ionic currents in multidrug resistant K562 human leukemic cells.
2005 Sep
Absorption of folate by Caco-2 cells is not affected by high glucose concentration.
2006 Dec 3
Appearance of segmental discrepancy of anion transport in rat distal colon.
2007 Aug
Functional ion channels in mouse bone marrow mesenchymal stem cells.
2007 Nov
The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2.
2008 Jan
Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons.
2010 Jan
Attenuating homologous recombination stimulates an AID-induced antileukemic effect.
2013 May 6
Functional swapping between transmembrane proteins TMEM16A and TMEM16F.
2014 Mar 14
Patents
Name Type Language
4,4'-DIISOTHIOCYANATO-2,2'-STILBENEDISULFONIC ACID
Common Name English
2,2'-(1,2-ETHENEDIYL)BIS(5-ISOTHIOCYANATOBENZENESULFONIC ACID)
Common Name English
DIDS
MI  
Common Name English
DIDS [MI]
Common Name English
Code System Code Type Description
CAS
53005-05-3
Created by admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
PRIMARY
MERCK INDEX
m4383
Created by admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
PRIMARY Merck Index
WIKIPEDIA
DIDS
Created by admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
PRIMARY
FDA UNII
QHR3Z2PN8M
Created by admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
PRIMARY
CHEBI
4286
Created by admin on Sat Dec 16 07:01:19 GMT 2023 , Edited by admin on Sat Dec 16 07:01:19 GMT 2023
PRIMARY
Definition References