Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2998 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12213051 |
1.0 µM [IC50] | ||
Target ID: GO:0006821 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3783658 |
2.0 µM [Ki] | ||
Target ID: P51798 Gene ID: 1186.0 Gene Symbol: CLCN7 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20830208 |
39.0 µM [IC50] |
PubMed
Title | Date | PubMed |
---|---|---|
Antiviral immunotoxins: antibody-mediated delivery of gelonin inhibits Pichinde virus replication in vitro. | 1991 Feb |
|
Inhibition of gp120-CD4 interaction and human immunodeficiency virus type 1 infection in vitro by pyridoxal 5'-phosphate. | 1994 Oct |
|
Chromium- and nickel-induced cytotoxicity in normal and transformed human keratinocytes: an investigation of pharmacological approaches to the prevention of Cr(VI)-induced cytotoxicity. | 1996 Feb |
|
Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | 1997 Sep-Oct |
|
Redox regulation of p53 during hypoxia. | 2000 Aug 10 |
|
Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4. | 2000 Sep 29 |
|
Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages. | 2002 Apr |
|
Urate transport via human PAH transporter hOAT1 and its gene structure. | 2003 Jan |
|
Tumour-specific activation of the sodium/iodide symporter gene under control of the glucose transporter gene 1 promoter (GTI-1.3). | 2003 May |
|
Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts. | 2004 Jul |
|
Molecular determinants of differential pore blocking of kidney CLC-K chloride channels. | 2004 Jun |
|
ATP binding cassette transporter ABC1 is required for the release of interleukin-1beta by P2X7-stimulated and lipopolysaccharide-primed mouse Schwann cells. | 2005 Mar |
|
Ionic currents in multidrug resistant K562 human leukemic cells. | 2005 Sep |
|
Chronic high glucose inhibits albumin reabsorption by lysosomal alkalinization in cultured porcine proximal tubular epithelial cells (LLC-PK1). | 2006 Jun |
|
Anion exchanger 2 mediates the action of arsenic trioxide. | 2006 Sep |
|
Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter. | 2007 Aug |
|
Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans. | 2007 Aug |
|
Activity and regulation of Na+-HCO3- cotransporter in immortalized spontaneously hypertensive rat and Wistar-Kyoto rat proximal tubular epithelial cells. | 2007 May |
|
Functional ion channels in mouse bone marrow mesenchymal stem cells. | 2007 Nov |
|
The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2. | 2008 Jan |
|
Pharmacologic blockade of chloride channel synergistically enhances apoptosis of chemotherapeutic drug-resistant cancer stem cells. | 2008 Sep 5 |
|
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. | 2009 Feb |
|
Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. | 2010 Jan |
|
Functional swapping between transmembrane proteins TMEM16A and TMEM16F. | 2014 Mar 14 |
Patents
Substance Class |
Mixture
Created
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Edited
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Record Version |
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m4383
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DIDS
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QHR3Z2PN8M
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