2-AMINOINDAN HYDROCHLORIDE

Cl.NC1CC2=C(C1)C=CC=C2

InChIKey=XEHNLVMHWYPNEQ-UHFFFAOYSA-N

InChI=1S/C9H11N.ClH/c10-9-5-7-3-1-2-4-8(7)6-9;/h1-4,9H,5-6,10H2;1H

Targets

Primary Target	Pharmacology	Potency
Alpha-2c adrenergic receptor 37 Target ID: CHEMBL1916 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Binding Agent 1064	41.0 nM [Ki]
Alpha-2b adrenergic receptor 27 Target ID: CHEMBL1942 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Binding Agent 1064	211.0 nM [Ki]
Alpha-2a adrenergic receptor 63 Target ID: CHEMBL1867 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Binding Agent 1064	134.0 nM [Ki]
Norepinephrine transporter 191 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Substrate 661	86.0 nM [EC50]
Dopamine transporter 180 Target ID: CHEMBL238 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30904940	Substrate 661	439.0 nM [EC50]

PubMed

Title	Date	PubMed
Copper-containing monooxygenases: enzymatic and biomimetic studies of the O-atom transfer catalysis.	2002 Apr	12069196
Safety, pharmacokinetics, and pharmacodynamics of CHF 3381, a novel N-methyl-D-aspartate antagonist, after single oral doses in healthy subjects.	2003 Aug	12953347
Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties.	2004 Dec 6	15501040
Indantadol, a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain.	2007 Sep	17786847
[Analysis of designer drugs detected in the products purchased in fiscal year 2006].	2008 Oct	18827471
Analgesic and anti-inflammatory activity of amifostine, DRDE-07, and their analogs, in mice.	2010 Feb	20606831
Analgesic effect of Lepidium sativum Linn. (Chandrashura) in experimental animals.	2010 Jul	22131742

Patents

Name

Type

Language

2-AMINOINDAN HYDROCHLORIDE

Common Name

English

NSC-78117

Code

English

1H-INDEN-2-AMINE, 2,3-DIHYDRO-, HYDROCHLORIDE (1:1)

Systematic Name

English

2-INDANAMINE, HYDROCHLORIDE

Systematic Name

English

2-AI (HYDROCHLORIDE)

Common Name

English

INDAN-2-YLAMINE HYDROCHLORIDE

Systematic Name

English

2-AMINOINDAN, HCL

Common Name

English

NSC-48663

Code

English

Code System Code Type Description

ECHA (EC/EINECS)

219-048-0