U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C21H23NO3.BrH
Molecular Weight 418.324
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROROXAN HYDROBROMIDE

SMILES

Br.O=C(CCN1CCC(C1)C2=CC=CC=C2)C3=CC4=C(OCCO4)C=C3

InChI

InChIKey=YRTLMJNPRCWOML-UHFFFAOYSA-N
InChI=1S/C21H23NO3.BrH/c23-19(17-6-7-20-21(14-17)25-13-12-24-20)9-11-22-10-8-18(15-22)16-4-2-1-3-5-16;/h1-7,14,18H,8-13,15H2;1H

HIDE SMILES / InChI
TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Pirroksan

Approved Use

Proroxan has been used as an antihypertensive and in the treatment of Ménière’s disease, motion sickness, and allergic dermatitis.
Primary
Pirroksan

Approved Use

Proroxan has been used as an antihypertensive and in the treatment of Ménière’s disease, motion sickness, and allergic dermatitis.
Primary
Pirroksan

Approved Use

Proroxan has been used as an antihypertensive and in the treatment of Ménière’s disease, motion sickness, and allergic dermatitis.
PubMed

PubMed

TitleDatePubMed
[Adrenergic component in the hepatotropic, carcinogenic effect of diethylnitrosamine].
1977 Apr
Patents

Sample Use Guides

Adults: tablets - 20 mg 2-3 times a day; injection - 2-3 ml per day; The maximum daily dose is 90 mg;
Route of Administration: Other
In Vitro Use Guide
Unknown
Name Type Language
PROROXAN HYDROBROMIDE
Common Name English
1-PROPANONE, 1-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-(3-PHENYL-1-PYRROLIDINYL)-, HYDROBROMIDE
Systematic Name English
1-PROPANONE, 1-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-(3-PHENYL-1-PYRROLIDINYL)-, HYDROBROMIDE (1:1)
Systematic Name English
Code System Code Type Description
FDA UNII
J48JGW5NHZ
Created by admin on Sat Dec 16 10:17:46 GMT 2023 , Edited by admin on Sat Dec 16 10:17:46 GMT 2023
PRIMARY
CAS
51758-99-7
Created by admin on Sat Dec 16 10:17:46 GMT 2023 , Edited by admin on Sat Dec 16 10:17:46 GMT 2023
PRIMARY
PUBCHEM
119057589
Created by admin on Sat Dec 16 10:17:46 GMT 2023 , Edited by admin on Sat Dec 16 10:17:46 GMT 2023
PRIMARY