Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C21H23NO3.BrH |
| Molecular Weight | 418.324 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Br.O=C(CCN1CCC(C1)C2=CC=CC=C2)C3=CC4=C(OCCO4)C=C3
InChI
InChIKey=YRTLMJNPRCWOML-UHFFFAOYSA-N
InChI=1S/C21H23NO3.BrH/c23-19(17-6-7-20-21(14-17)25-13-12-24-20)9-11-22-10-8-18(15-22)16-4-2-1-3-5-16;/h1-7,14,18H,8-13,15H2;1H
| Molecular Formula | C21H23NO3 |
| Molecular Weight | 337.4122 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | BrH |
| Molecular Weight | 80.912 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Proroxan is a non-selective а-adrenoblocker. Proroxan was found to prevent the development of hypertensive crises and improve cerebral bioelectrical parameters in most of hypertensive patients. Proroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | Pirroksan Approved UseProroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis. |
|||
| Primary | Pirroksan Approved UseProroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis. |
|||
| Primary | Pirroksan Approved UseProroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis. |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:17:46 GMT 2023
by
admin
on
Sat Dec 16 10:17:46 GMT 2023
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| Record UNII |
J48JGW5NHZ
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| Record Status |
Validated (UNII)
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| Record Version |
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J48JGW5NHZ
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51758-99-7
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119057589
Created by
admin on Sat Dec 16 10:17:46 GMT 2023 , Edited by admin on Sat Dec 16 10:17:46 GMT 2023
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
