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Details

Stereochemistry ACHIRAL
Molecular Formula C4H7N3O
Molecular Weight 113.1179
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CREATININE

SMILES

CN1CC(=O)N=C1N

InChI

InChIKey=DDRJAANPRJIHGJ-UHFFFAOYSA-N
InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

HIDE SMILES / InChI

Description

Creatinine is a product of metabolism of creatine phosphate, a molecule that serves as a rapidly mobilizable reserve of a brain and skeletal muscle. Creatinine is excreted by kidneys with little or no reabsorption. Serum creatinine is the most commonly used indicator of renal function.

CNS Activity

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Unknown
Inactive ingredient
AGELOC TRANSFORMATION

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Small amounts of creatinine are normally administered with food. In the study oral administration of up to 7g of creatinine does not lead to elevation of creatinine levels in the blood.
Route of Administration: Oral
In Vitro Use Guide
The blood level of creatinine is routinely measured by measurement devices. Method principles are based on a cascade of enzymatic reactions, followed by either photometric or electrochemical detection. Preferred sample types vary from whole blood to serum/plasma or both. Sample volumes range from 1 to 30 μL generally. A normal result for creatinine blood test is 0.7 to 1.3 mg/dL for men and 0.6 to 1.1 mg/dL for women.