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Details

Stereochemistry ACHIRAL
Molecular Formula C8H14NO
Molecular Weight 140.2029
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of FURTRETHONIUM

SMILES

C[N+](C)(C)CC1=CC=CO1

InChI

InChIKey=HEDXEAAVEOJUCR-UHFFFAOYSA-N
InChI=1S/C8H14NO/c1-9(2,3)7-8-5-4-6-10-8/h4-6H,7H2,1-3H3/q+1

HIDE SMILES / InChI
FURTRETHONIUM is an agonist of muscarinic acetylcholine receptors. It was used for the treatment of glaucoma.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Furmethide

Approved Use

Furtrethonum is a parasympathomimetic drug used for the treatment of glaucoma
Doses

Doses

DosePopulationAdverse events​
10 % 1 times / day multiple, ophthalmic
Dose: 10 %, 1 times / day
Route: ophthalmic
Route: multiple
Dose: 10 %, 1 times / day
Sources:
unhealthy
n = 21
Health Status: unhealthy
Condition: glaucoma
Population Size: 21
Sources:
Disc. AE: Dacryostenosis acquired...
AEs leading to
discontinuation/dose reduction:
Dacryostenosis acquired (71%)
Sources:
AEs

AEs

AESignificanceDosePopulation
Dacryostenosis acquired 71%
Disc. AE
10 % 1 times / day multiple, ophthalmic
Dose: 10 %, 1 times / day
Route: ophthalmic
Route: multiple
Dose: 10 %, 1 times / day
Sources:
unhealthy
n = 21
Health Status: unhealthy
Condition: glaucoma
Population Size: 21
Sources:
PubMed

PubMed

TitleDatePubMed
Glaucoma treatment by furnethide and diisopropylfluorophosphate.
1949 Jul
Patents

Patents

Name Type Language
FURTRETHONIUM
MI  
Common Name English
FURTRIMETHONIUM
Common Name English
FURTRETHONIUM [MI]
Common Name English
AMMONIUM, FURFURYLTRIMETHYL-
Systematic Name English
FURFURYLTRIMETHYLAMMONIUM
Systematic Name English
2-FURANMETHANAMINIUM, N,N,N-TRIMETHYL-
Systematic Name English
FURTRETONIUM
Common Name English
FURTRETHONIUM CATION
Common Name English
FURTRETHONIUM ION
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C47792
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
Code System Code Type Description
PUBCHEM
10938
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY
CAS
7618-86-2
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY
EPA CompTox
DTXSID50227048
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY
FDA UNII
AIQ630U6XO
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY
MESH
C028530
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY
MERCK INDEX
M5611
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY Merck Index
NCI_THESAURUS
C72790
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY
DRUG CENTRAL
3256
Created by admin on Wed Jul 05 22:59:46 UTC 2023 , Edited by admin on Wed Jul 05 22:59:46 UTC 2023
PRIMARY