Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H14NO.C6H5O3S |
| Molecular Weight | 297.37 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[N+](C)(C)CC1=CC=CO1.[O-]S(=O)(=O)C2=CC=CC=C2
InChI
InChIKey=IVNIBHOEODRCPK-UHFFFAOYSA-M
InChI=1S/C8H14NO.C6H6O3S/c1-9(2,3)7-8-5-4-6-10-8;7-10(8,9)6-4-2-1-3-5-6/h4-6H,7H2,1-3H3;1-5H,(H,7,8,9)/q+1;/p-1
| Molecular Formula | C8H14NO |
| Molecular Weight | 140.2029 |
| Charge | 1 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C6H5O3S |
| Molecular Weight | 157.167 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Doses
| Dose | Population | Adverse events |
|---|---|---|
10 % 1 times / day multiple, ophthalmic Dose: 10 %, 1 times / day Route: ophthalmic Route: multiple Dose: 10 %, 1 times / day Sources: |
unhealthy |
Disc. AE: Dacryostenosis acquired... AEs leading to discontinuation/dose reduction: Dacryostenosis acquired (71%) Sources: |
AEs
| AE | Significance | Dose | Population |
|---|---|---|---|
| Dacryostenosis acquired | 71% Disc. AE |
10 % 1 times / day multiple, ophthalmic Dose: 10 %, 1 times / day Route: ophthalmic Route: multiple Dose: 10 %, 1 times / day Sources: |
unhealthy |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors. | 1997-07 |
|
| Glaucoma treatment by furnethide and diisopropylfluorophosphate. | 1949-07 |
|
| The use of furmethide in comparison with pilocarpine and eserine for the treatment of glaucoma. | 1947-08 |
|
| Further studies on the use of furmethide in the treatment of glaucoma. | 1946-04 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:31:02 GMT 2025
by
admin
on
Mon Mar 31 22:31:02 GMT 2025
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| Record UNII |
EGN9KOM72T
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| Record Status |
Validated (UNII)
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| Record Version |
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m5611
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EGN9KOM72T
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3481-26-3
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15692623
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admin on Mon Mar 31 22:31:02 GMT 2025 , Edited by admin on Mon Mar 31 22:31:02 GMT 2025
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |