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Details

Stereochemistry ACHIRAL
Molecular Formula C5H6O5.C4H9N3O2
Molecular Weight 277.2313
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CREATINE ALPHA-KETOGLUTARATE

SMILES

CN(CC(O)=O)C(N)=N.OC(=O)CCC(=O)C(O)=O

InChI

InChIKey=VSQHMIFYITYXRG-UHFFFAOYSA-N
InChI=1S/C5H6O5.C4H9N3O2/c6-3(5(9)10)1-2-4(7)8;1-7(4(5)6)2-3(8)9/h1-2H2,(H,7,8)(H,9,10);2H2,1H3,(H3,5,6)(H,8,9)

HIDE SMILES / InChI
Creatine is an amino acid that occurs in vertebrate tissues and in urine. It is synthesized mainly in the liver from three different amino acids: arginine, glycine, and methionine. In skeletal muscles, which store 95% of it, creatine generally occurs as phosphocreatine. The rest is stored in the brain, heart, and testes. Creatine functions as part of the cell's energy shuttle. It is excreted as creatinine in the urine.

Approval Year

PubMed

PubMed

TitleDatePubMed
Acute quadriceps compartment syndrome and rhabdomyolysis in a weight lifter using high-dose creatine supplementation.
2000 Mar-Apr
Evolution and physiological roles of phosphagen systems.
2001
Parkinsonism and neck extensor myopathy: a new syndrome or coincidental findings?
2001 Feb
Release of muscle proteins after downhill running in male and female subjects.
2001 Feb
Serum concentrations of collagen degrading enzymes and their inhibitors after downhill running.
2001 Feb
Cardiac troponins and creatine kinase content of striated muscle in common laboratory animals.
2001 Feb
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
2001 Feb
Sensitivity of quantitative (1)H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus.
2001 Feb
Benefits of micronised Fenofibrate in type 2 diabetes mellitus subjects with good glycemic control.
2001 Feb 1
Leukocyte filtration in the early reperfusion phase on cardiopulmonary bypass reduces myocardial injury.
2001 Jan
Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability.
2001 Jan
Improving diagnostic yield in brain biopsy: coupling spectroscopic targeting with real-time needle placement.
2001 Jan
Plasma lipids and urinary albumin excretion rate in Type 1 diabetes mellitus: the EURODIAB IDDM Complications Study.
2001 Jan
Systemic effects of hyperthermic isolated lower limb perfusion with carboplatin and interferon-beta.
2001 Jan
Evaluation of the dystrophin-glycoprotein complex, alpha-actinin, dysferlin and calpain 3 in an autosomal recessive muscular dystrophy in Labrador retrievers.
2001 Jan
Recovery of muscles of old rats after hindlimb immobilisation by external fixation is impaired compared with those of young rats.
2001 Jan
Role of exercise and ascorbate on plasma antioxidant capacity in thoroughbred race horses.
2001 Jan
Win, place, show: creatine consumption and the price of winning.
2001 Jan
Prenatal programming of adult hypertension in the rat.
2001 Jan
Energetic driving forces are maintained in resting rat skeletal muscle after dietary creatine supplementation.
2001 Jan
Tissue engineering of functional cardiac muscle: molecular, structural, and electrophysiological studies.
2001 Jan
A genome scan for renal function among hypertensives: the HyperGEN study.
2001 Jan
Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies.
2001 Jan 20
Assessment of coronary reperfusion in patients with myocardial infarction using fatty acid binding protein concentrations in plasma.
2001 Mar
Patents
Name Type Language
CREATINE ALPHA-KETOGLUTARATE
Common Name English
PENTANEDIOIC ACID, 2-OXO-, COMPD. WITH N-(AMINOIMINOMETHYL)-N-METHYLGLYCINE (1:1)
Common Name English
GLYCINE, N-(AMINOIMINOMETHYL)-N-METHYL-, 2-OXOPENTANEDIOATE (1:1)
Common Name English
CREATINE AKG
Common Name English
Code System Code Type Description
CAS
315669-78-4
Created by admin on Sat Dec 16 17:24:34 GMT 2023 , Edited by admin on Sat Dec 16 17:24:34 GMT 2023
PRIMARY
PUBCHEM
9925587
Created by admin on Sat Dec 16 17:24:34 GMT 2023 , Edited by admin on Sat Dec 16 17:24:34 GMT 2023
PRIMARY
FDA UNII
9WV7GXM6T5
Created by admin on Sat Dec 16 17:24:34 GMT 2023 , Edited by admin on Sat Dec 16 17:24:34 GMT 2023
PRIMARY