Details
Stereochemistry | ACHIRAL |
Molecular Formula | 2C7H5O2.Zn |
Molecular Weight | 307.636 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Zn++].[O-]C(=O)C1=CC=CC=C1.[O-]C(=O)C2=CC=CC=C2
InChI
InChIKey=JDLYKQWJXAQNNS-UHFFFAOYSA-L
InChI=1S/2C7H6O2.Zn/c2*8-7(9)6-4-2-1-3-5-6;/h2*1-5H,(H,8,9);/q;;+2/p-2
Zinc Benzoate is an organic metal salt in a white powder form. It is very slightly soluble in water. Zinc Benzoate is commonly used in food and feed additives as a preservative and source of zinc. It is antiseptic, anti-animalcule and anti-freezing agent used in food, medicine, tobacco, plating, printing and dyeing.
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14581168
Curator's Comment: Zinc benzoate, which inhibits MAO-A activity, is easily incorporated in DDI water by boiling polystyrene and also may be a contaminating environmental chemical compound that alters the levels of serotonin and norepinephrine in the central nervous system. Demonstrated in monkeys.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: MAO-A, Macaca fuscata Sources: https://www.ncbi.nlm.nih.gov/pubmed/14581168 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
PubMed
Title | Date | PubMed |
---|---|---|
Zinc benzoate, a contaminating environmental compound derived from polystyrene resin inhibits A-type monoamine oxidase. | 2003 Nov 30 |
|
Synthesis of inorganic-organic layered compounds using immiscible liquid-liquid systems under the distribution law. | 2010 Oct 19 |
|
Crystal structure, spectral, thermal and dielectric studies of a new zinc benzoate single crystal. | 2012 Nov |
|
The application of bioactive compounds from the food industry to control mold growth in indoor waterborne coatings. | 2013 Apr 1 |
Patents
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14581168
The effects of zinc benzoate at concentrations of
0.01–10ug/ml on MAO activity in the mitochondria
of monkey brain were studied in vitro. The MAO-A
activity was inhibited dose-dependently with 5-HT as
substrate, and the residual activity of MAO-A was
about 10% in the presence of 10ug/ml of zinc benzoate.
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PARENT (SALT/SOLVATE)
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD