Details
Stereochemistry | ACHIRAL |
Molecular Formula | 2C7H5O2.Zn |
Molecular Weight | 307.636 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Zn++].[O-]C(=O)C1=CC=CC=C1.[O-]C(=O)C2=CC=CC=C2
InChI
InChIKey=JDLYKQWJXAQNNS-UHFFFAOYSA-L
InChI=1S/2C7H6O2.Zn/c2*8-7(9)6-4-2-1-3-5-6;/h2*1-5H,(H,8,9);/q;;+2/p-2
Molecular Formula | Zn |
Molecular Weight | 65.409 |
Charge | 2 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C7H5O2 |
Molecular Weight | 121.1134 |
Charge | -1 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Zinc Benzoate is an organic metal salt in a white powder form. It is very slightly soluble in water. Zinc Benzoate is commonly used in food and feed additives as a preservative and source of zinc. It is antiseptic, anti-animalcule and anti-freezing agent used in food, medicine, tobacco, plating, printing and dyeing.
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14581168
Curator's Comment: Zinc benzoate, which inhibits MAO-A activity, is easily incorporated in DDI water by boiling polystyrene and also may be a contaminating environmental chemical compound that alters the levels of serotonin and norepinephrine in the central nervous system. Demonstrated in monkeys.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: MAO-A, Macaca fuscata Sources: https://www.ncbi.nlm.nih.gov/pubmed/14581168 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14581168
The effects of zinc benzoate at concentrations of
0.01–10ug/ml on MAO activity in the mitochondria
of monkey brain were studied in vitro. The MAO-A
activity was inhibited dose-dependently with 5-HT as
substrate, and the residual activity of MAO-A was
about 10% in the presence of 10ug/ml of zinc benzoate.
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:48:28 GMT 2023
by
admin
on
Fri Dec 15 19:48:28 GMT 2023
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Record UNII |
6S1JO8U0CK
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Record Status |
Validated (UNII)
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Record Version |
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PARENT -> SALT/SOLVATE |