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Details

Stereochemistry ACHIRAL
Molecular Formula 2C7H5O2.Zn
Molecular Weight 307.6229
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZINC BENZOATE

SMILES

c1ccc(cc1)C(=O)[O-].c1ccc(cc1)C(=O)[O-].[ZnH2+2]

InChI

InChIKey=JDLYKQWJXAQNNS-UHFFFAOYSA-L
InChI=1S/2C7H6O2.Zn/c2*8-7(9)6-4-2-1-3-5-6;/h2*1-5H,(H,8,9);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula Zn
Molecular Weight 65.3956
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C7H5O2
Molecular Weight 121.1137
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Zinc Benzoate is an organic metal salt in a white powder form. It is very slightly soluble in water. Zinc Benzoate is commonly used in food and feed additives as a preservative and source of zinc. It is antiseptic, anti-animalcule and anti-freezing agent used in food, medicine, tobacco, plating, printing and dyeing.

CNS Activity

Curator's Comment:: Zinc benzoate, which inhibits MAO-A activity, is easily incorporated in DDI water by boiling polystyrene and also may be a contaminating environmental chemical compound that alters the levels of serotonin and norepinephrine in the central nervous system. Demonstrated in monkeys.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: MAO-A, Macaca fuscata
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Zinc benzoate, a contaminating environmental compound derived from polystyrene resin inhibits A-type monoamine oxidase.
2003 Nov 30
Synthesis of inorganic-organic layered compounds using immiscible liquid-liquid systems under the distribution law.
2010 Oct 19
Crystal structure, spectral, thermal and dielectric studies of a new zinc benzoate single crystal.
2012 Nov
The application of bioactive compounds from the food industry to control mold growth in indoor waterborne coatings.
2013 Apr 1
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
The effects of zinc benzoate at concentrations of 0.01–10ug/ml on MAO activity in the mitochondria of monkey brain were studied in vitro. The MAO-A activity was inhibited dose-dependently with 5-HT as substrate, and the residual activity of MAO-A was about 10% in the presence of 10ug/ml of zinc benzoate.
Substance Class Chemical
Created
by admin
on Sat Jun 26 10:35:26 UTC 2021
Edited
by admin
on Sat Jun 26 10:35:26 UTC 2021
Record UNII
6S1JO8U0CK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZINC BENZOATE
Systematic Name English
BENZOIC ACID, ZINC SALT
Common Name English
NSC-176118
Code English
Code System Code Type Description
CAS
553-72-0
Created by admin on Sat Jun 26 10:35:26 UTC 2021 , Edited by admin on Sat Jun 26 10:35:26 UTC 2021
PRIMARY
FDA UNII
6S1JO8U0CK
Created by admin on Sat Jun 26 10:35:26 UTC 2021 , Edited by admin on Sat Jun 26 10:35:26 UTC 2021
PRIMARY
ECHA (EC/EINECS)
209-047-3
Created by admin on Sat Jun 26 10:35:26 UTC 2021 , Edited by admin on Sat Jun 26 10:35:26 UTC 2021
PRIMARY
PUBCHEM
160523
Created by admin on Sat Jun 26 10:35:26 UTC 2021 , Edited by admin on Sat Jun 26 10:35:26 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE