Details
Stereochemistry | RACEMIC |
Molecular Formula | C21H23NO3.ClH |
Molecular Weight | 373.873 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.O=C(CCN1CCC(C1)C2=CC=CC=C2)C3=CC4=C(OCCO4)C=C3
InChI
InChIKey=QQZPGRDQMBPRFY-UHFFFAOYSA-N
InChI=1S/C21H23NO3.ClH/c23-19(17-6-7-20-21(14-17)25-13-12-24-20)9-11-22-10-8-18(15-22)16-4-2-1-3-5-16;/h1-7,14,18H,8-13,15H2;1H
Proroxan is a non-selective а-adrenoblocker. Proroxan was found to prevent the development of hypertensive crises and improve cerebral bioelectrical parameters in most of hypertensive patients. Proroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: CHEMBL2094251 |
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Target ID: CHEMBL2095158 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | Pirroksan Approved UseProroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis. |
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Primary | Pirroksan Approved UseProroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis. |
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Primary | Pirroksan Approved UseProroxan has been used as an antihypertensive and in the treatment
of Ménière’s disease, motion sickness, and allergic dermatitis. |
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29713
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admin on Fri Dec 15 15:48:11 GMT 2023 , Edited by admin on Fri Dec 15 15:48:11 GMT 2023
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36302
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C009143
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300000044227
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C84120
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694Z9P44G4
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CHEMBL1395610
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33025-33-1
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DTXSID70954647
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ACTIVE MOIETY
SUBSTANCE RECORD