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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H14N5O8P
Molecular Weight 363.2206
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FOSDENOPTERIN

SMILES

NC1=NC(=O)C2=C(N[C@@H]3O[C@@H]4COP(O)(=O)O[C@@H]4C(O)(O)[C@@H]3N2)N1

InChI

InChIKey=CZAKJJUNKNPTTO-AJFJRRQVSA-N
InChI=1S/C10H14N5O8P/c11-9-14-6-3(7(16)15-9)12-4-8(13-6)22-2-1-21-24(19,20)23-5(2)10(4,17)18/h2,4-5,8,12,17-18H,1H2,(H,19,20)(H4,11,13,14,15,16)/t2-,4-,5+,8-/m1/s1

HIDE SMILES / InChI

Description

Cyclic pyranopterin monophosphate is a precursor to molybdenum cofactor, which is required for the enzyme activity of sulfite oxidase, xanthine dehydrogenase/oxidase, and aldehyde oxidase. The drug is being investigated in severe molybdenum cofactor deficiency type A. In a clinical study, intravenous administration of the drug resulted in greatly improved neurodevelopmental outcome when started sufficiently early.

Approval Year

Name Type Language
CYCLIC PYRANOPTERIN MONOPHOSPHATE
Preferred Name English
FOSDENOPTERIN
INN  
Official Name English
PRECURSOR Z
Common Name English
C(PMP)
Common Name English
1,3,2-DIOXAPHOSPHORINO(4',5':5,6)PYRANO(3,2-G)PTERIDIN-10(4H)-ONE, 8-AMINO-4A,5A,6,7,11,11A,12,12A-OCTAHYDRO-2,12,12-TRIHYDROXY-, 2-OXIDE, (4AR,5AR,11AR,12AS)-
Common Name English
CPMP
Common Name English
FOSDENOPTERIN [INN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 291209
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
EU-Orphan Drug EU/3/10/777
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
Code System Code Type Description
CAS
150829-29-1
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
PUBCHEM
16061579
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
EVMPD
SUB197148
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
WIKIPEDIA
Cyclic pyranopterin monophosphate
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
INN
11150
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY