Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H14N5O8P |
| Molecular Weight | 363.2206 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12COP(O)(=O)O[C@]1([H])C(O)(O)[C@]3([H])NC4=C(NC(N)=NC4=O)N[C@]3([H])O2
InChI
InChIKey=CZAKJJUNKNPTTO-AJFJRRQVSA-N
InChI=1S/C10H14N5O8P/c11-9-14-6-3(7(16)15-9)12-4-8(13-6)22-2-1-21-24(19,20)23-5(2)10(4,17)18/h2,4-5,8,12,17-18H,1H2,(H,19,20)(H4,11,13,14,15,16)/t2-,4-,5+,8-/m1/s1
Cyclic pyranopterin monophosphate is a precursor to molybdenum cofactor, which is required for the enzyme activity of sulfite oxidase, xanthine dehydrogenase/oxidase, and aldehyde oxidase. The drug is being investigated in severe molybdenum cofactor deficiency type A. In a clinical study, intravenous administration of the drug resulted in greatly improved neurodevelopmental outcome when started sufficiently early.
Approval Year
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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FDA ORPHAN DRUG |
291209
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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EU-Orphan Drug |
EU/3/10/777
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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| Code System | Code | Type | Description | ||
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2531288
Created by
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150829-29-1
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SUB197148
Created by
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C175065
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100000182803
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Cyclic pyranopterin monophosphate
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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4X7K2681Y7
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11150
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DTXSID90934067
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admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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GH-135
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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4X7K2681Y7
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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59648
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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52994
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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60210
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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135463437
Created by
admin on Sat Dec 16 06:43:49 GMT 2023 , Edited by admin on Sat Dec 16 06:43:49 GMT 2023
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PRIMARY |
ACTIVE MOIETY
METABOLITE ACTIVE (PARENT)
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
