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Cyclic pyranopterin monophosphate is a precursor to molybdenum cofactor, which is required for the enzyme activity of sulfite oxidase, xanthine dehydrogenase/oxidase, and aldehyde oxidase. The drug is being investigated in severe molybdenum cofactor deficiency type A. In a clinical study, intravenous administration of the drug resulted in greatly improved neurodevelopmental outcome when started sufficiently early.

Approval Year

Substance Class
Concept
Record UNII
X41B5W735T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FOSDENOPTERIN HYDROBROMIDE
USAN  
Official Name English
NULIBRY
Brand Name English
ALXN-1101 HYDROBROMIDE DIHYDRATE
Code English
FOSDENOPTERIN HYDROBROMIDE [USAN]
Common Name English
CYCLIC PYRANOPTERIN MONOPHOSPHATE MONOHYDROBROMIDE DIHYDRATE
Common Name English
FOSDENOPTERIN HYDROBROMIDE DIHYDRATE
Common Name English
1,3,2-DIOXAPHOSPHORINO(4',5':5,6)PYRANO(3,2-G)PTERIDIN-10(4H)-ONE, 8-AMINO-4A,5A,6,9,11,11A,12,12A-OCTAHYDRO-2,12,12-TRIHYDROXY-, 2-OXIDE, HYDROBROMIDE, HYDRATE (1:1:2), (4AR,5AR,11AR,12AS)-
Systematic Name English
Code System Code Type Description
NCI_THESAURUS
C174941
Created by admin on Sat Jun 26 12:49:05 UTC 2021 , Edited by admin on Sat Jun 26 12:49:05 UTC 2021
PRIMARY
CAS
2301083-34-9
Created by admin on Sat Jun 26 12:49:05 UTC 2021 , Edited by admin on Sat Jun 26 12:49:05 UTC 2021
PRIMARY
PUBCHEM
145722612
Created by admin on Sat Jun 26 12:49:05 UTC 2021 , Edited by admin on Sat Jun 26 12:49:05 UTC 2021
PRIMARY
EVMPD
SUB197141
Created by admin on Sat Jun 26 12:49:05 UTC 2021 , Edited by admin on Sat Jun 26 12:49:05 UTC 2021
PRIMARY
FDA UNII
X41B5W735T
Created by admin on Sat Jun 26 12:49:05 UTC 2021 , Edited by admin on Sat Jun 26 12:49:05 UTC 2021
PRIMARY
This is a non-substance concept
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY
This is a non-substance concept