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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H14N5O8P
Molecular Weight 363.2206
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FOSDENOPTERIN

SMILES

NC1=NC(=O)C2=C(N[C@@H]3O[C@@H]4COP(O)(=O)O[C@@H]4C(O)(O)[C@@H]3N2)N1

InChI

InChIKey=CZAKJJUNKNPTTO-AJFJRRQVSA-N
InChI=1S/C10H14N5O8P/c11-9-14-6-3(7(16)15-9)12-4-8(13-6)22-2-1-21-24(19,20)23-5(2)10(4,17)18/h2,4-5,8,12,17-18H,1H2,(H,19,20)(H4,11,13,14,15,16)/t2-,4-,5+,8-/m1/s1

HIDE SMILES / InChI

Molecular Formula C10H14N5O8P
Molecular Weight 363.2206
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Cyclic pyranopterin monophosphate is a precursor to molybdenum cofactor, which is required for the enzyme activity of sulfite oxidase, xanthine dehydrogenase/oxidase, and aldehyde oxidase. The drug is being investigated in severe molybdenum cofactor deficiency type A. In a clinical study, intravenous administration of the drug resulted in greatly improved neurodevelopmental outcome when started sufficiently early.

Approval Year

Substance Class Chemical
Created
by admin
on Mon Oct 21 19:56:35 UTC 2019
Edited
by admin
on Mon Oct 21 19:56:35 UTC 2019
Record UNII
4X7K2681Y7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYCLIC PYRANOPTERIN MONOPHOSPHATE
Preferred Name English
FOSDENOPTERIN
INN  
Official Name English
PRECURSOR Z
Common Name English
C(PMP)
Common Name English
1,3,2-DIOXAPHOSPHORINO(4',5':5,6)PYRANO(3,2-G)PTERIDIN-10(4H)-ONE, 8-AMINO-4A,5A,6,7,11,11A,12,12A-OCTAHYDRO-2,12,12-TRIHYDROXY-, 2-OXIDE, (4AR,5AR,11AR,12AS)-
Common Name English
CPMP
Common Name English
FOSDENOPTERIN [INN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 291209
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
EU-Orphan Drug EU/3/10/777
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
Code System Code Type Description
CAS
150829-29-1
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
PUBCHEM
16061579
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
EVMPD
SUB197148
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
WIKIPEDIA
Cyclic pyranopterin monophosphate
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
INN
11150
Created by admin on Mon Oct 21 19:56:35 UTC 2019 , Edited by admin on Mon Oct 21 19:56:35 UTC 2019
PRIMARY
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ACTIVE MOIETY