U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C12H20N2O3S.ClH
Molecular Weight 308.825
Optical Activity ( + )
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEXSOTALOL HYDROCHLORIDE

SMILES

Cl.CC(C)NC[C@@H](O)C1=CC=C(NS(C)(=O)=O)C=C1

InChI

InChIKey=VIDRYROWYFWGSY-UTONKHPSSA-N
InChI=1S/C12H20N2O3S.ClH/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17;/h4-7,9,12-15H,8H2,1-3H3;1H/t12-;/m1./s1

HIDE SMILES / InChI
Dexsotalol is an isomer of antiarrhythmic drug d,l-sotalol, but in opposite to drug, it increases the incidence of arrhythmias

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance.
2003 Oct
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
DEXSOTALOL HYDROCHLORIDE
USAN   WHO-DD  
USAN  
Official Name English
(+)-(S)-4'-(1-HYDROXY-2-(ISOPROPYLAMINO)ETHYL)METHANESULFONANILIDE MONOHYDROCHLORIDE
Systematic Name English
DEXSOTALOL HYDROCHLORIDE [USAN]
Common Name English
BMY-05763-1-D
Code English
(+)-SOTALOL HYDROCHLORIDE
Common Name English
D-SOTALOL HYDROCHLORIDE
Common Name English
(+)-MJ 1999
Code English
SOTALOL HYDROCHLORIDE, D-
Common Name English
BMY-05763-1D
Code English
(+)-4'-(2-ISOPROPYLAMINO-1-HYDROXYETHYL)METHANESULFONANILIDE HYDROCHLORIDE
Common Name English
METHANESULFONAMIDE, N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-, MONOHYDROCHLORIDE
Common Name English
SOTALOL HYDROCHLORIDE, (S)-
Common Name English
METHANESULFONAMIDE, N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
Dexsotalol hydrochloride [WHO-DD]
Common Name English
Code System Code Type Description
USAN
GG-57
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
PRIMARY
ChEMBL
CHEMBL252312
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
PRIMARY
PUBCHEM
165245
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
PRIMARY
SMS_ID
300000038610
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
PRIMARY
NCI_THESAURUS
C166534
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
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EPA CompTox
DTXSID10196529
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
PRIMARY
CAS
4549-94-4
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
PRIMARY
FDA UNII
2328OK6Q6P
Created by admin on Fri Dec 15 15:16:33 GMT 2023 , Edited by admin on Fri Dec 15 15:16:33 GMT 2023
PRIMARY