Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C6H8O7.Na.Sb |
| Molecular Weight | 336.873 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Sb+3].OC[C@@H]([O-])[C@@H]([O-])[C@H]([O-])[C@@H](O)C([O-])=O
InChI
InChIKey=JEKOQEIHGHQVEI-ZBHRUSISSA-M
InChI=1S/C6H9O7.Na.Sb/c7-1-2(8)3(9)4(10)5(11)6(12)13;;/h2-5,7,11H,1H2,(H,12,13);;/q-3;+1;+3/p-1/t2-,3-,4+,5-;;/m1../s1
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL2176840 |
|||
Target ID: CHEMBL2755 |
|||
Target ID: Q27778 Gene ID: NA Gene Symbol: PFK Target Organism: Schistosoma mansoni (Blood fluke) |
200.0 µM [IC50] |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Curative | TRIOSTAM Approved UseFor the treatment of various types of a protozoal infection called leishmaniasis. |
PubMed
| Title | Date | PubMed |
|---|---|---|
| USE OF "TRIOSTAM" (SODIUM ANTIMONYLGLUCONATE) AGAINST RECTAL SCHISTOSOMIASIS IN TANGANYIKA. | 1964 Mar |
|
| THE INTENSIVE TREATMENT OF RECTAL SCHISTOSOMIASIS WITH TRIOSTAM (SODIUM ANTIMONYLGLUCONATE). | 1965 Jan |
|
| Stokes-Adams attacks following sodium antimonylgluconate (Triostam). | 1966 Nov 19 |
|
| Comparative trials of antimonial drugs in urinary schistosomiasis. | 1968 |
|
| Trypanothione reductase from Leishmania donovani. Purification, characterisation and inhibition by trivalent antimonials. | 1995 Jun 1 |
Sample Use Guides
The drug should be used at a total dosage not exceeding 25 mg. per kg.
and a daily dosage not exceeding 6 mg. per kg.,
Route of Administration:
Intravenous
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SUB127002
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1U72RT57II
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CHEMBL2108095
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100000153150
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m1962
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235-699-3
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12550-17-3
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76968133
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PARENT (SALT/SOLVATE)
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
