U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H4N4O2
Molecular Weight 152.1109
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of XANTHINE

SMILES

O=C1NC2=C(NC=N2)C(=O)N1

InChI

InChIKey=LRFVTYWOQMYALW-UHFFFAOYSA-N
InChI=1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

HIDE SMILES / InChI

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Xanthine stone in the urinary bladder of a male child.
1999
Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells.
1999 Mar
Free radicals and brain damage in the newborn.
2001
Doxofylline: a new generation xanthine bronchodilator devoid of major cardiovascular adverse effects.
2001
Abnormal Ca2+ signalling in vascular endothelial cells from spontaneously hypertensive rats: role of free radicals.
2001 Apr
Properties of tomato powders as additives for food fortification and stabilization.
2001 Apr
Effect of reactive oxygen species on fetal lung maturation.
2001 Apr
Xanthine oxidase in eutopic and ectopic endometrium in endometriosis and adenomyosis.
2001 Apr
Caffeine metabolism before and after liver transplantation.
2001 Feb
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
2001 Feb
6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation.
2001 Feb 1
Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides.
2001 Jan
Products of metabolic activation of the antitumor drug ledakrin (nitracrine) in vitro.
2001 Jan
Induction of cell death in arabidopsis by superoxide in combination with salicylic acid or with protein synthesis inhibitors.
2001 Jan 1
Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia.
2001 Jan 1
Purine nucleotide catabolism in rat liver: labelling of uric acid and allantoin after treatment with oxonic acid and allopurinol.
2001 Jan 26
Lung preconditioning with N-acetyl-L-cysteine prevents reperfusion injury after liver no flow-reflow: a dose-response study.
2001 Jan 27
The characteristics of nucleobase transport and metabolism by the perfused sheep choroid plexus.
2001 Jan 5
Hyperoxia inhibits oxidant-induced apoptosis in lung epithelial cells.
2001 Jan 5
Molecular cloning of a cDNA coding for feline liver xanthine dehydrogenase.
2001 Mar
Inhibition of xanthine and monoamine oxidases by stilbenoids from Veratrum taliense.
2001 Mar
Oxidative stress and vascular damage in hypertension.
2001 Mar
Enhancement of antioxidant and anti-inflammatory activities of bioflavonoid rutin by complexation with transition metals.
2001 Mar 15
Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80.
2001 Mar 2
Cytochrome C is a potent catalyst of dichlorofluorescin oxidation: implications for the role of reactive oxygen species in apoptosis.
2001 Mar 23
Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer.
2001 Mar 7
Patents

Patents

06413975
1
06616955
10
06649600
13
07579348
1
Name Type Language
XANTHINE
INCI   MI   WHO-DD  
INCI  
Official Name English
XANTHINE [INCI]
Common Name English
9H-PURINE-2,6(1H,3H)-DIONE
Systematic Name English
XANTHIC OXIDE
Common Name English
3,9-DIHYDRO-1H-PURINE-2,6-DIONE
Systematic Name English
1H,3H,9H-XANTHINE
Common Name English
1H-PURINE-2,6-DIOL
Systematic Name English
3,9-DIHYDROPURINE-2,6-DIONE
Systematic Name English
NSC-14664
Code English
Xanthine [WHO-DD]
Common Name English
1H-PURINE-2,6-DIONE, 3,7-DIHYDRO-
Systematic Name English
2,6-DIOXO-1,2,3,6-TETRAHYDROPURINE
Systematic Name English
2,6-DIOXOPURINE
Systematic Name English
XANTHINE [MI]
Common Name English
1H,3H,7H-XANTHINE
Common Name English
PURINE-2,6(1H,3H)-DIONE
Systematic Name English
1H-PURINE-2,6-DIONE, 3,9-DIHYDRO-
Systematic Name English
Classification Tree Code System Code
LOINC 41227-0
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 75144-6
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 38371-1
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 75129-7
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 3131-0
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 3132-8
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 41230-4
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
EPA PESTICIDE CODE 116900
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 72897-2
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 41228-8
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
LOINC 58036-5
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
Code System Code Type Description
MESH
D019820
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
EVMPD
SUB15733MIG
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
PUBCHEM
1188
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
FDA UNII
1AVZ07U9S7
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
RXCUI
1311085
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY RxNorm
SMS_ID
100000076747
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
WIKIPEDIA
XANTHINE
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
DAILYMED
1AVZ07U9S7
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
NSC
14664
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
CHEBI
48517
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
EPA CompTox
DTXSID4035120
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
CAS
69-89-6
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
ECHA (EC/EINECS)
200-718-6
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
CHEBI
17712
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
DRUG BANK
DB02134
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
MERCK INDEX
m11527
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY Merck Index
CHEBI
15318
Created by admin on Fri Dec 15 15:09:57 GMT 2023 , Edited by admin on Fri Dec 15 15:09:57 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of XANTHINE
METABOLITE (PARENT)
Structure of URIC ACID
PARENT (METABOLITE)
Structure of HYPOXANTHINE
PARENT (METABOLITE)
Structure of NELARABINE
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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