XANTHINE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H4N4O2
Molecular Weight	152.1109
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1NC2=C(NC=N2)C(=O)N1

InChI

InChIKey=LRFVTYWOQMYALW-UHFFFAOYSA-N

InChI=1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

HIDE SMILES / InChI

Molecular Formula	C5H4N4O2
Molecular Weight	152.1109
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Xanthine stone in the urinary bladder of a male child.	1999	10743702
Pharmacotherapeutical reduction of post-hypoxic-ischemic brain injury in the newborn.	2001	11275665
Free radicals and brain damage in the newborn.	2001	11275648
Reactive oxygen species (ROS)-generating oxidases in the normal rabbit cornea and their involvement in the corneal damage evoked by UVB rays.	2001 Apr	11332708
Photoreactivation of alloxanthine-inhibited xanthine oxidase.	2001 Apr	11332041
Effect of reactive oxygen species on fetal lung maturation.	2001 Apr	11301161
Xanthine oxidase in eutopic and ectopic endometrium in endometriosis and adenomyosis.	2001 Apr	11287035
The chemical work of Alexander and Jane Marcet.	2001 Apr	11274044
Insight into the chemistry of flavin reduction and oxidation in Escherichia coli dihydroorotate dehydrogenase obtained by rapid reaction studies.	2001 Apr 10	11284694
Synthesis and structure-activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors.	2001 Apr 9	11294382
Intralobular heterogeneity of oxidative stress and cell death in ischemia-reperfused rat liver.	2001 Feb	11162032
Determination of urinary methylated purine pattern by high-performance liquid chromatography.	2001 Feb 10	11232859
Effects of food intake and oxidative stress on intestinal lesions caused by meloxicam and piroxicam in rats.	2001 Feb 23	11230998
Production of free radicals measured by spin trapping during operations for stenosis of the carotid artery.	2001 Jan	11213819
Induction of cell death in arabidopsis by superoxide in combination with salicylic acid or with protein synthesis inhibitors.	2001 Jan 1	11134900
Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.	2001 Jan 1	11134892
The effects of delta sleep-inducing peptide on the intensity of lipid peroxidation and xanthine oxidase activity in rat tissues during cold stress.	2001 Jan-Feb	11265821
Enhanced sensitivity of Cypridina luciferin analogue (CLA) chemiluminescence for the detection of *O2(-) with non-ionic detergents.	2001 Jan-Feb	11180658
The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers.	2001 Mar	11327632
Inhibition of xanthine and monoamine oxidases by stilbenoids from Veratrum taliense.	2001 Mar	11301865
Experimental and theoretical microdialysis studies of in situ metabolism.	2001 Mar	11237334
Effects of reactive oxygen species on proliferation of Chinese hamster lung fibroblast (V79) cells.	2001 Mar 15	11295367
Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells.	2001 Mar 15	11295358
7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties.	2001 Mar 16	11108716
Redox-sensitive regulation of lox-1 gene expression in vascular endothelium.	2001 Mar 2	11237717
ESR studies on reaction of saccharide with the free radicals generated from the xanthine oxidase/hypoxanthine system containing iron.	2001 Mar 9	11248231
Xanthine oxidase inhibitory activity of selected Australian native plants.	2001 May	11297862

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:48:43 GMT 2025` Edited by `admin` on `Mon Mar 31 17:48:43 GMT 2025`
Record UNII	1AVZ07U9S7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

XANTHINE

Official Name

English

NSC-14664

Preferred Name

English

9H-PURINE-2,6(1H,3H)-DIONE

Systematic Name

English

XANTHIC OXIDE

Common Name

English

3,9-DIHYDRO-1H-PURINE-2,6-DIONE

Systematic Name

English

1H,3H,9H-XANTHINE

Common Name

English

1H-PURINE-2,6-DIOL

Systematic Name

English

3,9-DIHYDROPURINE-2,6-DIONE

Systematic Name

English

Xanthine [WHO-DD]

Common Name

English

1H-PURINE-2,6-DIONE, 3,7-DIHYDRO-

Systematic Name

English

2,6-DIOXO-1,2,3,6-TETRAHYDROPURINE

Systematic Name

English

2,6-DIOXOPURINE

Systematic Name

English

XANTHINE [MI]

Common Name

English

1H,3H,7H-XANTHINE

Common Name

English

PURINE-2,6(1H,3H)-DIONE

Systematic Name

English

1H-PURINE-2,6-DIONE, 3,9-DIHYDRO-

Systematic Name

English

Classification Tree Code System Code

LOINC

41227-0