Details
Stereochemistry | ACHIRAL |
Molecular Formula | C5H4N4O2 |
Molecular Weight | 152.1109 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1NC2=C(NC=N2)C(=O)N1
InChI
InChIKey=LRFVTYWOQMYALW-UHFFFAOYSA-N
InChI=1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
Molecular Formula | C5H4N4O2 |
Molecular Weight | 152.1109 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Pharmacotherapeutical reduction of post-hypoxic-ischemic brain injury in the newborn. | 2001 |
|
Free radicals and brain damage in the newborn. | 2001 |
|
Doxofylline: a new generation xanthine bronchodilator devoid of major cardiovascular adverse effects. | 2001 |
|
Reactive oxygen species (ROS)-generating oxidases in the normal rabbit cornea and their involvement in the corneal damage evoked by UVB rays. | 2001 Apr |
|
Photoreactivation of alloxanthine-inhibited xanthine oxidase. | 2001 Apr |
|
Abnormal Ca2+ signalling in vascular endothelial cells from spontaneously hypertensive rats: role of free radicals. | 2001 Apr |
|
Serum xanthine oxidase in human liver disease. | 2001 Apr |
|
Effect of hypoxia, oxidative stress and lipopolysaccharides on the release of prostaglandins and cytokines from human term placental explants. | 2001 Apr |
|
Properties of tomato powders as additives for food fortification and stabilization. | 2001 Apr |
|
Analysis of peroxynitrite reactions with guanine, xanthine, and adenine nucleosides by high-pressure liquid chromatography with electrochemical detection: C8-nitration and -oxidation. | 2001 Apr |
|
Effect of reactive oxygen species on fetal lung maturation. | 2001 Apr |
|
Xanthine oxidase in eutopic and ectopic endometrium in endometriosis and adenomyosis. | 2001 Apr |
|
Functional characterization of a maize purine transporter by expression in Aspergillus nidulans. | 2001 Apr |
|
The chemical work of Alexander and Jane Marcet. | 2001 Apr |
|
Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia. | 2001 Apr |
|
Insight into the chemistry of flavin reduction and oxidation in Escherichia coli dihydroorotate dehydrogenase obtained by rapid reaction studies. | 2001 Apr 10 |
|
Effects of tocopheryl quinone on the heart: model experiments with xanthine oxidase, heart mitochondria, and isolated perfused rat hearts. | 2001 Apr 15 |
|
Mutation of human molybdenum cofactor sulfurase gene is responsible for classical xanthinuria type II. | 2001 Apr 20 |
|
Phosphorylation of xanthine dehydrogenase/oxidase in hypoxia. | 2001 Apr 27 |
|
Synthesis and structure-activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors. | 2001 Apr 9 |
|
Effects of L-arginine cardioplegia on myocardium. | 2001 Feb |
|
Prevention of deleterious effects of reperfusion injury using one-week high-dose allopurinol. | 2001 Feb |
|
Caffeine metabolism before and after liver transplantation. | 2001 Feb |
|
Evaluation of health aspects of kojic acid in food. | 2001 Feb |
|
Characterization of DNA damage at purine residues in oligonucleotides and calf thymus DNA induced by the mutagen 1-nitrosoindole-3-acetonitrile. | 2001 Feb |
|
Cerebral ischemia in humans after traumatic brain injury. | 2001 Feb |
|
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury. | 2001 Feb |
|
A simple technique for the simultaneous determination of molecular weight and activity of superoxide dismutase using SDS-PAGE. | 2001 Feb 26 |
|
Xanthine oxidase activity and blood glutathione redox ratio in infants and children with septic shock syndrome. | 2001 Jan |
|
Effect of poly ICLC treatment on hepatic oxidative stress and antioxidant defense indices in Plasmodium yoelii nigeriensis infected mice. | 2001 Jan-Feb |
|
The effects of delta sleep-inducing peptide on the intensity of lipid peroxidation and xanthine oxidase activity in rat tissues during cold stress. | 2001 Jan-Feb |
|
Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues. | 2001 Jul 6 |
|
Tautomeric energetics of xanthine oxidase substrates: xanthine, 2-oxo-6-methylpurine, and lumazine. | 2001 Mar |
|
The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers. | 2001 Mar |
|
Antagonism of free-radical-induced damage of adlay seed and its antiproliferative effect in human histolytic lymphoma U937 monocytic cells. | 2001 Mar |
|
Molecular cloning of a cDNA coding for feline liver xanthine dehydrogenase. | 2001 Mar |
|
Inhibition of xanthine and monoamine oxidases by stilbenoids from Veratrum taliense. | 2001 Mar |
|
Aryl hydrocarbon receptor (AhR)-mediated induction of xanthine oxidase/xanthine dehydrogenase activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin. | 2001 Mar |
|
Effects of reactive oxygen species on proliferation of Chinese hamster lung fibroblast (V79) cells. | 2001 Mar 15 |
|
Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells. | 2001 Mar 15 |
|
Enhancement of antioxidant and anti-inflammatory activities of bioflavonoid rutin by complexation with transition metals. | 2001 Mar 15 |
|
Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury. | 2001 Mar 15 |
|
Cytochrome C is a potent catalyst of dichlorofluorescin oxidation: implications for the role of reactive oxygen species in apoptosis. | 2001 Mar 23 |
|
Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer. | 2001 Mar 7 |
|
Asafoetida inhibits early events of carcinogenesis: a chemopreventive study. | 2001 Mar 9 |
|
ESR studies on reaction of saccharide with the free radicals generated from the xanthine oxidase/hypoxanthine system containing iron. | 2001 Mar 9 |
|
Uric acid in cachectic and noncachectic patients with chronic heart failure: relationship to leg vascular resistance. | 2001 May |
|
Xanthine oxidase inhibitory activity of selected Australian native plants. | 2001 May |
|
Miniaturized amperometric biosensor based on xanthine oxidase for monitoring hypoxanthine in cell culture media. | 2001 May 1 |
|
Atrial natriuretic peptide inhibits tumor necrosis factor-alpha production by interferon-gamma-activated macrophages via suppression of p38 mitogen-activated protein kinase and nuclear factor-kappa B activation. | 2001 May 5 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Jul 05 22:41:40 UTC 2023
by
admin
on
Wed Jul 05 22:41:40 UTC 2023
|
Record UNII |
1AVZ07U9S7
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
LOINC |
41227-0
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
75144-6
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
38371-1
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
75129-7
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
3131-0
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
3132-8
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
41230-4
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
EPA PESTICIDE CODE |
116900
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
72897-2
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
41228-8
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
||
|
LOINC |
58036-5
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
D019820
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
SUB15733MIG
Created by
admin on Wed Jul 05 22:41:40 UTC 2023 , Edited by admin on Wed Jul 05 22:41:40 UTC 2023
|
PRIMARY | |||
|
1188
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
1AVZ07U9S7
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
1311085
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | RxNorm | ||
|
100000076747
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
XANTHINE
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
1AVZ07U9S7
Created by
admin on Wed Jul 05 22:41:40 UTC 2023 , Edited by admin on Wed Jul 05 22:41:40 UTC 2023
|
PRIMARY | |||
|
14664
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
48517
Created by
admin on Wed Jul 05 22:41:40 UTC 2023 , Edited by admin on Wed Jul 05 22:41:40 UTC 2023
|
PRIMARY | |||
|
DTXSID4035120
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
69-89-6
Created by
admin on Wed Jul 05 22:41:40 UTC 2023 , Edited by admin on Wed Jul 05 22:41:40 UTC 2023
|
PRIMARY | |||
|
200-718-6
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
17712
Created by
admin on Wed Jul 05 22:41:40 UTC 2023 , Edited by admin on Wed Jul 05 22:41:40 UTC 2023
|
PRIMARY | |||
|
DB02134
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | |||
|
M11527
Created by
admin on Wed Jul 05 22:41:41 UTC 2023 , Edited by admin on Wed Jul 05 22:41:41 UTC 2023
|
PRIMARY | Merck Index | ||
|
15318
Created by
admin on Wed Jul 05 22:41:40 UTC 2023 , Edited by admin on Wed Jul 05 22:41:40 UTC 2023
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
PARENT -> METABOLITE |
|
||
|
METABOLITE -> PARENT |
|
||
|
PARENT -> METABOLITE |
MINOR
|
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |
|