PYRITIDIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H27N7
Molecular Weight	437.5395
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	2

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC(NC2=CC3=C(C=C2)C4=C(C=C(N)C=C4)[N+](C)=C3C5=CC=C(N)C=C5)=NC(N)=[N+]1C

InChI

InChIKey=ATUKMAKBUDAKLO-UHFFFAOYSA-P

InChI=1S/C26H25N7/c1-15-12-24(31-26(29)32(15)2)30-19-9-11-20-21-10-8-18(28)13-23(21)33(3)25(22(20)14-19)16-4-6-17(27)7-5-16/h4-14H,1-3H3,(H5,27,28,29,30,31)/p+2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13831995 | https://www.ncbi.nlm.nih.gov/pubmed/13983883 | https://www.ncbi.nlm.nih.gov/pubmed/13739946

Pyritidium (also known as Prothidium) is a Phenanthridinium derivative with powerful prophylactic activity against cattle trypanosomiasis. Prothidium dibromide was used for the treatment of sleeping sickness in man and nagana in cattle. Pyritidium is thought to have antiviral properties and to interfere with the synthesis of nucleic acids in a variety of organisms.

Approval Year

PubMed

Title	Date	PubMed
Suramin complexes. X. Comparison of the prophylactic activity of prothidium-suramin complex and prothidium bromide in West African Zebu cattle.	1962 Dec	13983883

Patents

Name

Type

Language

PYRITIDIUM

Systematic Name

English

PYRITIDIUM ION

Common Name

English

PYRITHIDIUM

Common Name

English

PYRITIDIUM CATION

Common Name

English

3-AMINO-8-((2-AMINO-6-METHYL-4-PYRIMIDINYL)AMINO)-6-(P-AMINOPHENYL)-5-METHYLPHENANTHRIDINIUM

Common Name

English

PHENANTHRIDINIUM, 3-AMINO-8-((2-AMINO-1,6-DIMETHYL-4(1H)-PYRIMIDINYLIDENE)AMINO)-6-(4-AMINOPHENYL)-5-METHYL-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C277