PYRITIDIUM BROMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H27N7.2Br
Molecular Weight	597.347
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].[Br-].CC1=[N+](C)C(N)=NC(NC2=CC3=C(C=C2)C4=C(C=C(N)C=C4)[N+](C)=C3C5=CC=C(N)C=C5)=C1

InChI

InChIKey=IXNYZBNLCCQASS-UHFFFAOYSA-N

InChI=1S/C26H25N7.2BrH/c1-15-12-24(31-26(29)32(15)2)30-19-9-11-20-21-10-8-18(28)13-23(21)33(3)25(22(20)14-19)16-4-6-17(27)7-5-16;;/h4-14H,1-3H3,(H5,27,28,29,30,31);2*1H

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C26H25N7
Molecular Weight	435.5236
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13831995 | https://www.ncbi.nlm.nih.gov/pubmed/13983883 | https://www.ncbi.nlm.nih.gov/pubmed/13739946

Pyritidium (also known as Prothidium) is a Phenanthridinium derivative with powerful prophylactic activity against cattle trypanosomiasis. Prothidium dibromide was used for the treatment of sleeping sickness in man and nagana in cattle. Pyritidium is thought to have antiviral properties and to interfere with the synthesis of nucleic acids in a variety of organisms.

Approval Year

PubMed

Title	Date	PubMed
Suramin complexes. X. Comparison of the prophylactic activity of prothidium-suramin complex and prothidium bromide in West African Zebu cattle.	1962-12	13983883

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:28:25 GMT 2025` Edited by `admin` on `Mon Mar 31 18:28:25 GMT 2025`
Record UNII	3K01419ADP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PYRITHIDIUM BROMIDE

Preferred Name

English

PYRITIDIUM BROMIDE

Official Name

English

PHENANTHRIDINIUM, 3-AMINO-6-(4-AMINOPHENYL)-8-((1,2-DIHYDRO-2-IMINO-1,6-DIMETHYL-4-PYRIMIDINYL)AMINO)-5-METHYL-, BROMIDE, HYDROBROMIDE (1:1:1)

Systematic Name

English

PYRITHIDIUM BROMIDE [MART.]

Common Name

English

PROTHIDIUM

Brand Name

English

pyritidium bromide [INN]

Common Name

English

RD 2801

Code

English

3-AMINO-8-((2-AMINO-6-METHYL-4-PYRIMIDINYL)AMINO)-6-(P-AMINOPHENYL)-5-METHYLPHENANTHRIDINIUM BROMIDE 1'-METHOBROMIDE

Common Name

English

RD-2801

Code

English

Code System Code Type Description

MESH

C004795