PYRITIDIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H27N7
Molecular Weight	437.5395
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	2

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC(NC2=CC3=C(C=C2)C4=C(C=C(N)C=C4)[N+](C)=C3C5=CC=C(N)C=C5)=NC(N)=[N+]1C

InChI

InChIKey=ATUKMAKBUDAKLO-UHFFFAOYSA-P

InChI=1S/C26H25N7/c1-15-12-24(31-26(29)32(15)2)30-19-9-11-20-21-10-8-18(28)13-23(21)33(3)25(22(20)14-19)16-4-6-17(27)7-5-16/h4-14H,1-3H3,(H5,27,28,29,30,31)/p+2

HIDE SMILES / InChI

Molecular Formula	C26H25N7
Molecular Weight	435.5236
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13831995 | https://www.ncbi.nlm.nih.gov/pubmed/13983883 | https://www.ncbi.nlm.nih.gov/pubmed/13739946

Pyritidium (also known as Prothidium) is a Phenanthridinium derivative with powerful prophylactic activity against cattle trypanosomiasis. Prothidium dibromide was used for the treatment of sleeping sickness in man and nagana in cattle. Pyritidium is thought to have antiviral properties and to interfere with the synthesis of nucleic acids in a variety of organisms.

Approval Year

PubMed

Title	Date	PubMed
Suramin complexes. X. Comparison of the prophylactic activity of prothidium-suramin complex and prothidium bromide in West African Zebu cattle.	1962 Dec	13983883

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:39:09 GMT 2023` Edited by `admin` on `Fri Dec 15 15:39:09 GMT 2023`
Record UNII	0PFV70949S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PYRITIDIUM

Systematic Name

English

PYRITIDIUM ION

Common Name

English

PYRITHIDIUM

Common Name

English

PYRITIDIUM CATION

Common Name

English

3-AMINO-8-((2-AMINO-6-METHYL-4-PYRIMIDINYL)AMINO)-6-(P-AMINOPHENYL)-5-METHYLPHENANTHRIDINIUM

Common Name

English

PHENANTHRIDINIUM, 3-AMINO-8-((2-AMINO-1,6-DIMETHYL-4(1H)-PYRIMIDINYLIDENE)AMINO)-6-(4-AMINOPHENYL)-5-METHYL-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C277