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Search results for dactinomycin in Related Substance Name (approximate match)
Showing 1 - 3 of 3 results
Status:
US Approved Rx
(2017)
Source:
ANDA203385
(2017)
Source URL:
First approved in 1964
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Dactinomycin (actinomycin D) was isolated from Streptomyces by Selman Waksman in 1940s. The antibiotic shows anti-cancer activity; it was approved by FDA for the treatment of different cancer conditions among which are Ewing's sarcoma, Wilm's tumor, gestational trophoblastic disease, etc. Dactinomycin exerts its action by binding to DNA (preferably to GC motif) and thus inhibiting transcription.
Status:
US Approved Rx
(2013)
First approved in 1958
Class:
MIXTURE