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Search results for atazanavir in Reference Text / Citation (approximate match)
Showing 1 - 10 of 10 results
Status:
US Approved Rx
(2015)
Source:
NDA205395
(2015)
Source URL:
First approved in 2012
Source:
NDA203100
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Cobicistat (GS-9350) is a potent, and selective inhibitor of human cytochrome P450 3A (CYP3A) enzymes. Cobicistat is a pharmacokinetic booster of several antiretrovirals. TYBOST (cobicistat) is indicated to increase systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
Status:
US Approved Rx
(2020)
Source:
ANDA209717
(2020)
Source URL:
First approved in 2003
Source:
NDA021567
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Atazanavir is the first once-daily protease inhibitor for the treatment of human immunodeficiency virus type 1 infection and should be used only in combination therapy, as part of a highly active antiretroviral therapy (HAART) regimen. In addition to being the most potent protease inhibitor in vitro, atazanavir has a distinct cross-resistance profile that does not confer resistance to other protease inhibitors. However, resistance to other protease inhibitors often confers clinically relevant resistance to atazanavir.
Status:
US Approved Rx
(2020)
Source:
ANDA209717
(2020)
Source URL:
First approved in 2003
Source:
NDA021567
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Atazanavir is the first once-daily protease inhibitor for the treatment of human immunodeficiency virus type 1 infection and should be used only in combination therapy, as part of a highly active antiretroviral therapy (HAART) regimen. In addition to being the most potent protease inhibitor in vitro, atazanavir has a distinct cross-resistance profile that does not confer resistance to other protease inhibitors. However, resistance to other protease inhibitors often confers clinically relevant resistance to atazanavir.