U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Mon Oct 21 19:44:29 UTC 2019
Edited
by admin
on Mon Oct 21 19:44:29 UTC 2019
Protein Sub Type
Sequence Type COMPLETE
Record UNII
0RFO7VC96N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A1
Common Name English
UDP-GLUCURONOSYLTRANSFERASE 1A1
Common Name English
HUGT1A1
Common Name English
UDP-GLUCURONOSYLTRANSFERASE 1-1
Systematic Name English
UGT-1A1
Common Name English
HUMAN URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A1
Systematic Name English
UGT1A1
Common Name English
Code System Code Type Description
CAS
400706-63-0
Created by admin on Mon Oct 21 19:44:30 UTC 2019 , Edited by admin on Mon Oct 21 19:44:30 UTC 2019
PRIMARY
UNIPROT
P22309
Created by admin on Mon Oct 21 19:44:30 UTC 2019 , Edited by admin on Mon Oct 21 19:44:30 UTC 2019
PRIMARY
WIKIPEDIA
UDP GLUCURONOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1
Created by admin on Mon Oct 21 19:44:30 UTC 2019 , Edited by admin on Mon Oct 21 19:44:30 UTC 2019
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_77
N 1_270
N 1_322
Related Record Type Details
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> TRANSPORTER
MINOR
INHIBITOR -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
NON-SUBSTRATE -> METABOLIC ENZYME
in vitro study results indicate that pasireotide is not a substrate, inhibitor, or inducer for metabolic isozymes including UGT1A1 particularly at the proposed dosing range.
INHIBITOR -> METABOLIC ENZYME
IC50
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
IC50
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
IC50
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
MINOR
IC50
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MAJOR
SUBSTRATE -> METABOLIC ENZYME
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL