Search results for "ORPHAN DRUG|Designated/Withdrawn|Treatment of glioma" in comments (approximate match)
Showing 1 - 2 of 2 results
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Talampanel (TLP) was developed as a noncompetitive (allosteric) antagonist of the AMPA receptor. Talampanel does not act directly on the AMPA receptor, but at an allosteric site referred to as the GYKI receptor. Talampanel is being studied in the tre...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Galunisertib is a potent inhibitor of TGF beta type 1 receptor. The drug is under clinical development for the treatment of different cancers: pancreatic, hepatocellular, breast, rectal, prostate etc. and reached phase 2/3 in patients with myelodyspl...