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Restrict the search for
cetirizine
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There is one exact (name or code) match for cetirizine
Status:
US Approved Rx
(2018)
Source:
ANDA210719
(2018)
Source URL:
First approved in 1988
Source:
ANDA077170
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Cetirizine, a human metabolite of hydroxyzine, is an antihistamine; its principal effects are mediated via selective inhibition of peripheral H1 receptors. It is indicated for the relief of nasal and non-nasal symptoms associated with seasonal or perennial allergic rhinitis, hay fever and chronic idiopathic urticaria. Commonly reported adverse reactions of cetirizine include headache, dry mouth and drowsiness or fatigue. Pharmacokinetic interaction studies with Cetirizine in adults were conducted with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. No interactions were observed.
Status:
US Approved Rx
(2018)
Source:
ANDA210719
(2018)
Source URL:
First approved in 1988
Source:
ANDA077170
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Cetirizine, a human metabolite of hydroxyzine, is an antihistamine; its principal effects are mediated via selective inhibition of peripheral H1 receptors. It is indicated for the relief of nasal and non-nasal symptoms associated with seasonal or perennial allergic rhinitis, hay fever and chronic idiopathic urticaria. Commonly reported adverse reactions of cetirizine include headache, dry mouth and drowsiness or fatigue. Pharmacokinetic interaction studies with Cetirizine in adults were conducted with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. No interactions were observed.
Status:
US Approved Rx
(2013)
Source:
ANDA090362
(2013)
Source URL:
First approved in 1995
Source:
NDA022064
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Levocetirizine is the active enantiomer of cetirizine. It is inverse agonist of H1 receptors. Levocetirizine hydrochloride was approved for treatment of Allergic Rhinitis and Chronic Idiopathic Urticaria.
Status:
US Approved Rx
(2008)
Source:
ANDA040804
(2008)
Source URL:
First approved in 1956
Source:
ATARAX by ROERIG
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The sedative properties of hydroxyzine occur at the subcortical level of the CNS. Secondary to its central anticholinergic actions, hydroxyzine may be effective as an antiemetic. It is used for symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested.
Status:
Investigational
Source:
NCT00849264: Phase 2 Interventional Completed Hepatocellular Carcinoma
(2008)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
![Structure of 1-[(4-Chlorophenyl)phenylmethyl]-4-(phenylsulfonyl)piperazine](/img/49a94ae3-e184-462f-8bde-aa739c83b5a6.svg?size=200&context=kqqzjulzzx)
