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Restrict the search for
benzoyl peroxide
to a specific field?
Status:
Possibly Marketed Outside US
Source:
21 CFR 350
(2017)
Source URL:
First approved in 2017
Source:
21 CFR 350
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Dimethyl sebacate is used as a plasticizer, softening agent, solvent for cellulosic resin, polyethylene resin and synthetic rubber and especially as a major raw material to produce light stabilizers. It has a vegetal origin since it is processed from castor oil.
Status:
Possibly Marketed Outside US
Source:
M020
(2023)
Source URL:
First approved in 2017
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
Floriva by BonGeo Pharmaceuticals, Inc.
(2014)
Source URL:
First approved in 2014
Source:
Floriva by BonGeo Pharmaceuticals, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Levomefolate glucosamine is prodrug of Levomefolic acid. Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across the membranes including the blood-brain barrier into various tissues where it plays an essential role in the DNA synthesis, cysteine cycle and regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate (THF). Levomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound. It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the stability required for use as a supplement. Supplementation of levomefolic acid is desired over folic acid due to reduced potential for masking vitamin B12 deficiency symptoms.
Status:
Possibly Marketed Outside US
Source:
Aspirin with Apple Flavoring by MWI Veterinary Supply, Inc.
(2013)
Source URL:
First approved in 2013
Source:
Aspirin with Apple Flavoring by MWI Veterinary Supply, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Acetylsalicylsalicylic acid is a commonly occurring impurity in commercial acetylsalicylic acid preparations. It is considered to be immunogenic substance.
Status:
Possibly Marketed Outside US
Source:
21 CFR 348
(2013)
Source URL:
First approved in 2013
Source:
21 CFR 348
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
NCT03023514: Phase 4 Interventional Completed Women Infertility
(2015)
Source URL:
First approved in 2013
Source:
21 CFR 333D
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
THIOCTIC ACID, also known as alpha-lipoic acid, is a vitamin-like antioxidant that acts as a free-radical scavenger. It exists in two enantiomeric forms, R and S, being the R isoform an essential cofactor of four mitochondrial enzyme complexes. THIOCTIC ACID is available as an over-the-counter nutritional supplement and has been used nutritionally and clinically since the 1950s for various diseases and conditions.
Status:
Possibly Marketed Outside US
Source:
Skinprint Spot-On by The Skin Atelier, Inc.
(2012)
Source URL:
First approved in 2012
Source:
Skinprint Spot-On by The Skin Atelier, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Tetrapeptide-15 (Endomorphin-2) is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-2 increases pain thresholds in animal models of thermal pain and inhibits the formation of antibodies in other cellular models. In HUVECs, this peptide stimulates proliferation, migration, adhesion, and tube formation.
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2012)
Source URL:
First approved in 2012
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M021
(2012)
Source URL:
First approved in 2012
Source:
M021
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
NCT00955955: Phase 4 Interventional Completed Depression
(2009)
Source URL:
First approved in 2012
Source:
vitaMedMD One Rx by vitaMedMD
Source URL:
Class (Stereo):
CHEMICAL (EPIMERIC)
Targets:
Methylenetetrahydrofolate reductase (MTHFR) is an enzyme required for the formation of 5-methyltetrahydrofolate (5-MTHF), a form of folate able to cross the blood-brain barrier and which is necessary as a substrate for the remethylation of homocysteine to methionine by methionine synthase. Patients with severe MTHFR deficiency cannot make 5-MTHF and have extremely low levels in the CSF. Only treatment with oral 5-MTHF given as calcium mefolinate resulted in an increase in CSF 5-MTHF.
