Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H14O2S2 |
| Molecular Weight | 206.326 |
| Optical Activity | ( + ) |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CCCC[C@@H]1CCSS1
InChI
InChIKey=AGBQKNBQESQNJD-SSDOTTSWSA-N
InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
THIOCTIC ACID, also known as alpha-lipoic acid, is a vitamin-like antioxidant that acts as a free-radical scavenger. It exists in two enantiomeric forms, R and S, being the R isoform an essential cofactor of four mitochondrial enzyme complexes. THIOCTIC ACID is available as an over-the-counter nutritional supplement and has been used nutritionally and clinically since the 1950s for various diseases and conditions.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie. | 1997 Mar |
|
| Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. | 2009 Oct |
|
| Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases. | 2014 |
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DSLD |
2610 (Number of products:4)
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30314
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DTXSID20152651
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11156
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1200-22-2
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CHEMBL134342
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100000126090
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16494
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LIPOIC ACID
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DB00166
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SUB32811
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CHEMBL33864
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6112
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VLL71EBS9Z
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C171728
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43796
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VLL71EBS9Z
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m10749
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PRIMARY | Merck Index |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
