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Restrict the search for
dimethyl fumarate
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
FEZOLAMINE is a nontricyclic antidepressant. It acts as a serotonin, norepinephrine, and dopamine reuptake inhibitor, with a preference for the former neurotransmitter. It was found to be effective and well tolerated in clinical trials but was never marketed.
Class (Stereo):
CHEMICAL (MIXED)
Heptaverine was used as a spasmolytic agent. Information about the current use of this compound is not available.
Class (Stereo):
CHEMICAL (ACHIRAL)
Acequinoline (CB 4985) is an analgesic, antiinflammatory agent. It is also antirheumatic, antigout (antimalarial).
Class (Stereo):
CHEMICAL (ABSOLUTE)
Meteneprost (9-deoxo-16, 16-dimethyl-9-methylene PGE2) is a prostaglandin E2 analog. It exerts uterine-stimulating potency: meteneprost is able to both stimulate uterine contractions and dilate the cervical canal. It was studied as an abortifacient in early pregnancy.
Class (Stereo):
CHEMICAL (ACHIRAL)
Metibride was developed as an antilipidemic agent. Information about the current use of this compound is not available.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Trimoprostil is a synthetic prostaglandin E2 derivative and prostanoid receptor agonist, with potential gastric secretion inhibitor and antiulcerogenic activity. It has been shown to reduce hydrogen ion secretion, to enhance gastric bicarbonate secretion and to reduce aspirin-induced gastric mucosal injury. In contrast to many E prostaglandins, it does not lower the tone of the lower oesophageal sphincter. Trimoprostil was well tolerated and more effective than placebo in the treatment of mild to moderate symptomatic reflux oesophagitis. It may be protective to human squamous oesophageal mucosa. Trimoprostil was not as effective as cimetidine in the treatment of duodenal ulcer.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Flumoxonide, an acetal derivative, is a synthetic glucocorticoid corticosteroid, it is an antiinflammatory agent for topical use.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Cyclindole is a tryptamine derivative in which the aminoethyl side-chain has been cyclized. Clinical trials of the drug have demonstrated antidepressant activity. The drug also possesses neuroleptic properties and acts as an antagonist of the D2 receptor.
Status:
Investigational
Source:
USAN:IODOANTIPYRINE I 131 [USAN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Iodoantipyrine I-131 is a radiopharmaceutical nonsteroid anti-inflammatory compound evaluated for coronary blood flow measure and as a total body water marker. In vivo results suggested that soon after injection of 4-I131 AP (Iodoantipyrine I-131) in rats , significant and increasing quantities of the I131 tracer were detached from the antipyrine molecule in a form which is more diffusible than 4-I131 AP. Evidence for a similar phenomenon was seen in other species. There were qualitative differences in the behavior of antipyrine and 4-I131 AP when injected in animals, and these may invalidate the use of 4-I131 AP as a substitute for antipyrine in studies of body composition.
Class (Stereo):
CHEMICAL (ABSOLUTE)
FILIPIN is a complex of polyene macrolides obtained from Streptomyces filipinensis. The complex consists of four components: filipin I (4%), II (25%), III (53%), and IV (18%). Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. It is widely used as a marker for detection and quantification of cholesterol in cellular membranes.