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Details

Stereochemistry ACHIRAL
Molecular Formula C20H23N3
Molecular Weight 305.4167
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FEZOLAMINE

SMILES

CN(C)CCCN1C=C(C(=N1)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=NELSQLPTEWCHQW-UHFFFAOYSA-N
InChI=1S/C20H23N3/c1-22(2)14-9-15-23-16-19(17-10-5-3-6-11-17)20(21-23)18-12-7-4-8-13-18/h3-8,10-13,16H,9,14-15H2,1-2H3

HIDE SMILES / InChI
Molecular Formula C20H23N3
Molecular Weight 305.4167
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

FEZOLAMINE is a nontricyclic antidepressant. It acts as a serotonin, norepinephrine, and dopamine reuptake inhibitor, with a preference for the former neurotransmitter. It was found to be effective and well tolerated in clinical trials but was never marketed.

Originator

Sanofi Winthrop
12

Approval Year

Unknown
139,594

PubMed

Patents

JP2007505097A
25
JP2007513956A
15

Sample Use Guides

In Vivo Use Guide
Therapy initiation at 100 mg/day. Maintenance dosage usually ranged between 100 and 450 mg/day.
Route of Administration: Oral
Substance Class Chemical
Record UNII
1133E05F6C
Record Status Validated (UNII)
Record Version
NIH
NCATS
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