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Search results for "EPA PESTICIDE|CONVENTIONAL CHEMICAL" in comments (approximate match)
Status:
Investigational
Source:
INN:fenfluthrin [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
FENFLUTHRIN, a synthetic pyrethroid, is an obsolete insecticide that was used to control a variety of insect pests in food stores and for public hygiene purposes.
Class (Stereo):
CHEMICAL (ACHIRAL)
Carbophenothion is a highly toxic organophosphate insecticide used as a citrus pesticide called Trithion. Carbophenothion is a potent inhibitor of acetylcholinesterase, a neuromuscular enzyme that is widely needed for the normal function of insects, as well as people and many other animals. The Environmental Protection Agency (EPA) classifies it as a Restricted Pesticide (RUP). Carbophenothion is used in various brands, such as Trithion. This pesticide contains 80% Carbophenothion as its only active ingredient. Due to the widespread use of these organophosphates in the United States in the nineties, this was the most common cause of agricultural poisoning. Carbophenothion is used as an insecticide and acaricide, the main purpose of which is to protect citrus fruits, but also to protect the cotton from aphids (lice) and spider mites. In addition, it is used in combination with oil, and also as a pesticide against many other pests on fruits, nuts, vegetables, sorghum, corn, and others. In addition, it is used to combat animal parasites.
Class (Stereo):
CHEMICAL (ACHIRAL)
The organophosphate compound Naftalofos is an anthelmintic drug. In Australia it is approved for veterinary use. Naftalofos has been used for many years to control nematodes of livestock. Naftalofos boluses are used against nematodes of cattle. Naphthalophos (36.6 to 51.2 mg/kg) was also 93% efficient against the multiple resistant strains of Trichostrongylus colubriformis in sheep. Naphthalophos showed efficacy against Haemonchus contortus (> 99 %),Trichostrongylus axei (99.3 %), Teladorsagia circumcincta (97.8 %), Trichostrongylus colubriformis (99.2 %), Cooperia punctata/curticei/pectinata (90.4 %), Nematodirus spathiger (89.2 %) and Oesophagostomum venulosum/columbianum (93.7 %). Naphthalophos represents an effective therapeutic alternative for incorporation into worm control programmes.
Status:
Investigational
Source:
NCT00352729: Not Applicable Interventional Withdrawn Burns
(2006)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Investigational
Source:
NCT01871298: Not Applicable Interventional Completed Drug Abuse Illicit
(2014)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Investigational
Source:
NCT03860480: Not Applicable Interventional Completed Thoracic Surgery, Video-Assisted
(2018)
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
Status:
Investigational
Source:
NCT03301454: Phase 2 Interventional Unknown status Esophageal Cancer, Squamous Cell
(2018)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Imazethapyr is an imidazole compound used as a selective herbicide. It is applied preplant incorporated, preemergence, at cracking, and postemergence. The compound controls weeds by reducing the levels of three branched-chain aliphatic amino acids, isoleucine, leucine and valine, through the inhibition of aceto-hydroxyacid synthase, an enzyme common to the biosynthetic pathway for these amino acids. This inhibition causes a disruption in protein synthesis which, in turn, leads to an interference in DNA synthesis and cell growth. The compound is used to control grasses and broadleaved weeds including barnyardgrass, crabgrass, cocklebur, panicums, pigweeds, nightshade, mustard, smartweed, velvetleaf, jimsonweed, foxtails, seedling johnsongrass, lambsquarters, morningglory and others. Tolerant crops include soybeans, peanuts, dry and edible beans, peas, alfalfa and imidazolinone resistant/tolerant corn. Additional research is being conducted on other leguminous crops. Acetolactate synthase inhibition is the primary mechanism of action of imazethapyr (IM).
Status:
Investigational
Source:
NCT02020811: Not Applicable Interventional Unknown status Sepsis
(2013)
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
Cyproconazole is an azole fungicide, introduced to the market by Sandoz (now Syngenta). It is used to control a wide range of fungi on cereal crops, coffee, sugar beet, fruit trees, grapes, including rust on cereal crops, powdery mildew on cereal crops, fruit tree and grapes, and scab on apple. The cyproconazole structure exists in four stereoisomeric forms as two diastereoisomeric pairs of enantiomers. Cyproconazole is a 1:1 mixture of the two diastereomeric pairs, each of which is a 1:1 mixture of the enantiomers (i.e., all four stereoisomers are present in similar amounts). Cyproconazole inhibits the fungal enzyme eburicol 14-alpha-demethylase, which is involved in the biosynthesis of sterol, a component of a fungal cell wall.
Status:
Investigational
Source:
NCT01517256: Phase 3 Interventional Completed Chronic Pain
(2009)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Investigational
Source:
NCT00053443: Phase 2 Interventional Completed HIV Infections
Source URL:
Class (Stereo):
CHEMICAL (EPIMERIC)