U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 701 - 710 of 1355 results

Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(12)(iii) laxative:stool softener poloxamer 188
Source URL:

Class:
POLYMER

Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(21)(iv) ophthalmic:demulcents polyethylene glycol 6000
Source URL:

Class:
POLYMER

Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(20) weight control maltodextrin
Source URL:
First approved in 1984

Class:
POLYMER

Status:
US Previously Marketed
Source:
21 CFR 310.527(a) hair loss prevention polysorbate 20
Source URL:
First approved in 1978
Source:
60-Second Fluoride Pina Colada by Patterson Dental Supply Inc
Source URL:

Class:
POLYMER

Status:
US Previously Marketed
Source:
Sorboquel by White (Schering)
(1960)
Source URL:
First approved in 1960
Source:
Sorboquel by White (Schering)
Source URL:

Class:
POLYMER

Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(20) weight control alginic acid
Source URL:

Class:
POLYMER

Status:
US Previously Marketed
First approved in 1959
Source:
Emko Foam by Endo
Source URL:

Class:
POLYMER


Conditions:

Nonoxynol-9, is an organic compound that is used as a surfactant and vaginal spermicide used for contraception in spermicidal creams, jellies, foams, gel, and lubricants. It is also used in conjuction with other methods of contraception, including condoms, cervical caps and diaphragms. Nonoxynol-9 interacts with the lipids in the membranes of the acrosome and the midpiece of the sperm. The sperm membranes are lysed; the acrosome, neck and midpiece of the spermatozoa are loosened and then detached which results in their immobilization and death. Nonoxynol-9 offers no protection against sexually transmitted infections such as gonorrhoea, chlamydia and does not prevent HIV infection and may even favour infection if used frequently. A possible reason, is that nonoxynol-9 can disrupt the epithelium, or wall, of the vagina, thereby potentially facilitating invasion by an infective organism and virus. Nonoxynol-9 and related compounds are ingredients in various cleaning and cosmetic products.
Status:
US Previously Marketed
Source:
Levonor by Nordmark (Purdue Frederick)
(1957)
Source URL:
First approved in 1957
Source:
Levonor by Nordmark (Purdue Frederick)
Source URL:

Class:
POLYMER